A Practical Synthesis of Near-Infrared Benzannulated Xanthenoid Dyes

被引：2
|
作者：
Li, Jin [1 ]
Wei, Ruwei [1 ]
Zhang, Xiaodong [1 ]
Luo, Xiao [2 ]
Qian, Xuhong [1 ,2 ]
Yang, Youjun [1 ]
机构：
[1] East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China
[2] East China Normal Univ, Sch Chem & Mol Eng, Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev, Dongchuan Rd 500, Shanghai 200241, Peoples R China
来源：
SYNLETT | 2024年 / 35卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Key words fluorescence; near-infrared; benzoxanthene; stability; synthesis; FLUORESCENT DYES; RHODAMINE; BRIGHT; DERIVATIVES; DESIGN;
D O I：
10.1055/s-0042-1752719
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Near-infrared dyes are sought after for their potential in biomedical applications. Benzoxanthene dyes with a non-oxygen bridging atom are expected to exhibit longer absorption and emission wavelengths than their oxygen-containing counterparts, yet their synthesis remains unaddressed. Herein, we report the first syntheses of non -oxygen-bridged benzoxanthenes starting from a 7-bromo-2-aminonaphthalene derivative, and discuss their photophysical properties as well as their potential for in vivo imaging.
引用
收藏
页码：101 / 108
页数：8
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