Risk adjusted venous thromboembolism prophylaxis following pancreatic surgery

被引:3
|
作者
Pohl, Abigail [1 ]
Spaulding, Aaron C. [2 ]
Brennan, Emily R. [2 ]
Stauffer, John [3 ]
Hussain, Walid Akram [1 ]
Muraleedharan, Divya [1 ]
Colibaseanu, Dorin T. [4 ]
Edwards, Michael A. [1 ]
机构
[1] Mayo Clin, Dept Surg, Div Adv GI & Bariatr Surg, 4500 San Pablo Rd S Davis Bldg,3 North, Jacksonville, FL 32224 USA
[2] Mayo Clin, Robert D & Patricia E Kern Ctr, Div Hlth Care Delivery Res Jacksonville, Jacksonville, FL 32224 USA
[3] Mayo Clin, Dept Surg, Div Surg Oncol, Jacksonville, FL 32224 USA
[4] Mayo Clin, Dept Surg, Div Colorectal Surg, Jacksonville, FL 32224 USA
关键词
Pancreatectomy; Prophylaxis; Venous thromboembolism; POSTPANCREATECTOMY HEMORRHAGE; MEDICAL PATIENTS; CANCER-SURGERY; THROMBOPROPHYLAXIS; SAFETY; ANTICOAGULATION; ENOXAPARIN; EVENTS; DURATION; EFFICACY;
D O I
10.1007/s11239-023-02775-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study analyzes pancreatectomy cases performed between 2016 and 2021 to determine the impact of using Caprini guideline indicated VTE prophylaxis on VTE and bleeding complications. This is a retrospective study of cases performed in a single academic health care system, in which Caprini score and VTE prevention measures were determined retroactively and prevention practices binarized as appropriate or not appropriate. Univariate and multivariate analyses were performed of 1,299 pancreatectomy case. Most patients were stratified as high risk for postoperative VTE. Receiving appropriate VTE prophylaxis during admission was associated with a 3-fold reduction in VTE complications (0.82% vs. 2.64%, p=0.01) without increasing bleeding complications. All VTE complications occurring with 30-day (1.2%) and 90-day (2.7%) from hospital discharged occurred in those not receiving appropriate prophylaxis, and discharged bleeding complications were also not associated with receivng appropriate discharged VTE prophylaxis. The findings our the study are significant as it highlights the ongoing need for standardization in VTE risk assessment and prevention measures to increase compliance to risk adjusted VTE prevention practice guidelines, thus reducing preventable VTE complications and potentially associated morbidity and mortality.
引用
收藏
页码:604 / 616
页数:13
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