The relationship between aquaporins and skin diseases

被引：4
|
作者：
Liu, Jiahao [1 ]
Jin, Yingji [2 ]
Wei, Qinqin [1 ]
Hu, Yewei [1 ]
Liu, Liu [1 ]
Feng, Yiran [3 ]
Jin, Yuji [4 ]
Jiang, Yong [1 ]
机构：
[1] Jilin Med Univ, Dept Lab Med, Jilin 132013, Jilin, Peoples R China
[2] Yanbian Univ Hosp, Dept Dermatol, Yanji 133000, Jilin, Peoples R China
[3] Jilin Med Univ, Dept publ Hlth, Jilin 132013, Jilin, Peoples R China
[4] Jilin Med Univ, Dept Basic Med, Jilin 132013, Jilin, Peoples R China
来源：
EUROPEAN JOURNAL OF DERMATOLOGY | 2023年 / 33卷 / 04期
关键词：
aquaporin; physiological function; dermatosis; mechanism; WATER CHANNEL; BARRIER FUNCTION; CELL MIGRATION; SWEAT GLAND; EXPRESSION; GLYCEROL; IMMUNOLOCALIZATION; PROLIFERATION; KERATINOCYTES; HYDRATION;
D O I：
10.1684/ejd.2023.4526
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Aquaporins (AQPs) are a family of transmembrane channel proteins that can rapidly transport water molecules. The main subtype expressed in the epidermis and dermis is AQP3. Studies have confirmed that AQPs exert certain physiological functions in the skin, such as the maintenance of normal shape, the regulation of body temperature, moisturization and hydration, anti-aging, damage repair and antigen presentation. The abnormal expression of AQPs in skin cells can lead to a variety of skin diseases. This review summarizes the relevance of AQPs in dermatophysiological and pathophysiological processes, highlighting their potential as new drug targets for the treatment of skin diseases.
引用
收藏
页码：350 / 359
页数：10
相关论文
共 50 条
  • [1] The relationship between aquaporins and skin diseases
    Jiahao Liu
    Yingji Jin
    Qinqin Wei
    Yewei Hu
    Liu Liu
    Yiran Feng
    Yuji Jin
    Yong Jiang
    European Journal of Dermatology, 2023, 33 : 350 - 359
  • [2] Relationship between Aging-Related Skin Dryness and Aquaporins
    Ikarashi, Nobutomo
    Kon, Risako
    Kaneko, Miho
    Mizukami, Nanaho
    Kusunoki, Yoshiki
    Sugiyama, Kiyoshi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (07)
  • [3] RELATIONSHIP BETWEEN SKIN DISEASES AND BEHAVIOR VARIABLES
    VANDERSCHAAR, WW
    BRITISH JOURNAL OF DERMATOLOGY, 1986, 115 (05) : 586 - 586
  • [4] Expression of aquaporins in human skin keratinocytes: relationship to differentiation
    Verbavatz, J. M.
    Boury-Jamot, M.
    Cauchard, J-H
    Daraspe, J. E.
    Noblesse, E.
    Lezou, K.
    Dumas, M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 : S55 - S55
  • [5] Aquaporins Are One of the Critical Factors in the Disruption of the Skin Barrier in Inflammatory Skin Diseases
    Tricarico, Paola Maura
    Mentino, Donatella
    De Marco, Aurora
    Del Vecchio, Cecilia
    Garra, Sabino
    Cazzato, Gerardo
    Foti, Caterina
    Crovella, Sergio
    Calamita, Giuseppe
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (07)
  • [6] Advances in Relationship Between Alcohol Consumption and Skin Diseases
    Liu, Lin
    Chen, Jin
    CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY, 2023, 16 : 3785 - 3791
  • [7] Aquaporins in the Skin
    Patel, Ravi
    Heard, L. Kevin
    Chen, Xunsheng
    Bollag, Wendy B.
    AQUAPORINS, 2017, 969 : 173 - 191
  • [8] The Relationship Between Alzheimer's Disease and Skin Diseases: A Review
    Zhang, Hanlin
    Zhang, Dingyue
    Tang, Keyun
    Sun, Qiuning
    CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY, 2021, 14 : 1551 - 1560
  • [9] Relationship between chemical industrial environment and allergic skin diseases
    Fu, Shaohua
    Gong, Minli
    Xing, Guisheng
    ACTA BIOCHIMICA POLONICA, 2023, 70 (04) : 899 - 904
  • [10] Aquaporins in Renal Diseases
    He, Jinzhao
    Yang, Baoxue
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (02):
12345