ERK1/2 inhibition overcomes resistance to venetoclax in AML by altering mitochondrial metabolism

被引：0
|
作者：
Sharma, Priyanka
Ostermann, Lauren
Piya, Sujan
Baran, Natalia
Tyagi, Anudishi
Hindley, Christopher
Dao, Kim-Hien
Sims, Martin
Battula, V. Lokesh
Andreeff, Michael
Borthakur, Gautam
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 07期
关键词：
D O I：
10.1158/1538-7445.AM2023-3860
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3860
引用
收藏
页数：2
相关论文
共 50 条
  • [21] In vivo ERK1/2 reporting demonstrates the association and timing of ERK1/2 pathway reactivation and acquired resistance to RAF inhibitors
    Basile, Kevin J.
    Abel, Ethan V.
    Dadpey, Neda
    Aplin, Andrew E.
    CANCER RESEARCH, 2013, 73 (08)
  • [22] Chronic Inhibition of ERK1/2 Signaling Improves Disordered Bone and Mineral Metabolism in Hypophosphatemic (Hyp) Mice
    Zhang, Martin Y. H.
    Ranch, Daniel
    Pereira, Renata C.
    Armbrecht, Harvey J.
    Portale, Anthony A.
    Perwad, Farzana
    ENDOCRINOLOGY, 2012, 153 (04) : 1806 - 1816
  • [23] Inhibition of ERK1/2 Worsens Intestinal Ischemia/Reperfusion Injury
    Ban, Kechen
    Peng, Zhanglong
    Kozar, Rosemary A.
    PLOS ONE, 2013, 8 (09):
  • [24] Inhibition of ERK dimerization prevents the development of ERK1/2-mediated cardiac hypertrophy
    Huemmert, M.
    Vidal, M.
    Schmitt, J. P.
    Lohse, M. J.
    Lorenz, K.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2011, 383 : 26 - 26
  • [25] DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling
    Liu, Ruijie
    van Berlo, Jop H.
    York, Allen J.
    Vagnozzi, Ronald J.
    Maillet, Marjorie
    Molkentin, Jeffery D.
    CIRCULATION RESEARCH, 2016, 119 (02) : 249 - +
  • [26] ERK1/2 regulates hepatocyte Trib1 in response to mitochondrial dysfunction
    Soubeyrand, Sebastien
    Naing, Thet
    Martinuk, Amy
    McPherson, Ruth
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2013, 1833 (12): : 3405 - 3414
  • [27] Inhibition of fatty acid metabolism overcomes resistance to chemotherapy in DLBCL
    Berz, L.
    Czernilofsky, F.
    Angeli-Terzidou, A.
    Roider, T.
    Aljakouch, K.
    Naake, T.
    Poschet, G.
    Kliewer, G.
    Chapuy, B.
    Mueller-Tidow, C.
    Hell, R.
    Huber, W.
    Krijgsveld, J.
    Lu, J.
    Dietrich, S.
    ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 : 211 - 211
  • [28] Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML
    Bozhena, Jhas
    Sriskanthadevan, Shrivani
    Skrtic, Marko
    Sukhai, Mahadeo A.
    Voisin, Veronique
    Jitkova, Yulia
    Gronda, Marcela
    Hurren, Rose
    Wang, Xiaoming
    Laister, Rob C.
    Bader, Gary D.
    Minden, Mark D.
    Schimmer, Aaron D.
    BLOOD, 2012, 120 (21)
  • [29] DETRIMENTAL EFFECTS OF ERK1/2 INHIBITION ON THE INTESTINE DURING ISCHEMIA/REPERFUSION
    Ban, K.
    Peng, Z.
    Kozar, R. A.
    SHOCK, 2013, 39 : 37 - 38
  • [30] Antiproliferative effect of panaxynol on RASMCs via inhibition of ERK1/2 and CREB
    Jiang, Li-Ping
    Lu, Yang
    Nie, Bao-Ming
    Chen, Hong-Zhuan
    CHEMICO-BIOLOGICAL INTERACTIONS, 2008, 171 (03) : 348 - 354
12345