Impact of Prolonged SARS-CoV-2 Viral Shedding on COVID-19 Disease Outcome and Viral Dynamics

被引:0
|
作者
Sanyaolu, Adekunle [1 ,8 ]
Marinkovic, Aleksandra [2 ]
Prakash, Stephanie [2 ]
Balendra, Vyshnavy [2 ]
Hamdy, Kareem [2 ]
Haider, Nafees [3 ]
Abbasi, Abu Fahad [4 ]
Hosein, Zaheeda [5 ]
Younis, Kokab [6 ]
Smith, Stella [7 ]
Badaru, Olanrewaju [8 ]
Izurieta, Ricardo [9 ,10 ]
机构
[1] DYouville Univ, Buffalo, NY 14201 USA
[2] St James Sch Med, The Quarter 2640, Anguilla
[3] All St Univ, Sch Med, Roseau, Dominica
[4] Loyola Univ, Med Ctr, Maywood, IL USA
[5] Caribbean Med Univ, Willemstad, Curacao
[6] Univ Calgary, Calgary, AB, Canada
[7] Nigerian Inst Med Res, Lagos, Nigeria
[8] Fed Minist Hlth, Abuja, Nigeria
[9] Univ S Florida, Coll Publ Hlth, Global Communicable Dis, Tampa, FL USA
[10] Univ Amer, Quito 170513, Ecuador
关键词
COVID-19; SARS-CoV-2; Prolonged viral shedding; RNA shedding; Transmission;
D O I
10.1007/s12088-024-01238-1
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This article aimed to review the current literature on the impact of continuous shedding of the COVID-19 virus in infected patients in relation to disease outcome variables and viral dynamics. Electronic databases PubMed, Google Scholar, and MedlinePlus were searched using relevant keywords, restricting the selection to thirty-two peer-reviewed articles and four gray literatures from the WHO websites. Findings from this study showed that several variables such as sex, age, immune status, treatments, and vaccines were found to affect the outcomes associated with the COVID-19 virus shedding. These findings highlight the need for further research using longitudinal whole-genome sequencing of the virus and its variants to increase the understanding.
引用
收藏
页码:1416 / 1424
页数:9
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