Mepolizumab: Therapeutic strategy for a pediatric patient with eosinophilic granulomatosis with polyangiitis

被引：3

作者：

Ozola, Lota ^{[1
,2
]}

Aleksejeva, Elina ^{[1
,2
]}

Stoldere, Diana ^{[1
,2
,5
]}

Davidsone, Zane ^{[1
,2
]}

Santere, Ruta ^{[2
]}

Grantina, Ineta ^{[1
,2
]}

Cirule, Ieva ^{[1
,2
]}

Krams, Alvils ^{[3
,4
]}

机构：

[1] Riga Stradins Univ, Dept Paediat, Riga, Latvia

[2] Childrens Clin Univ Hosp, Clin Pediat Dis, Riga, Latvia

[3] Riga East Clin Univ Hosp, Ctr TB & Lung Dis, Riga, Latvia

[4] Univ Latvia, Dept Internal Med, Riga, Latvia

[5] Childrens Clin Univ Hosp, Vienibas gatve 45, LV-1004 Riga, Latvia

来源：

PEDIATRIC PULMONOLOGY | 2023年 / 58卷 / 03期

关键词：

mepolizumab in pediatrics; pediatric EGPA; small vessel vasculitis; CHURG-STRAUSS-SYNDROME; AMERICAN-COLLEGE; ALLERGIC GRANULOMATOSIS; CHILDHOOD; CLASSIFICATION; CRITERIA;

D O I：

10.1002/ppul.26249

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome) is classified as an antineutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis. It is a multisystem disorder and can affect every organ system. EGPA is a rare disease, with an estimated prevalence of 1/70,000-100,000 in Europe. As its onset usually occurs in adulthood, data from pediatric patients are limited. We present here a very rare practical EGPA clinical case involving a pediatric patient. Presently, data on mepolizumab usage in pediatric patients are limited, with only a few case reports published.

引用

页码：973 / 979

页数：7

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