A BISPECIFIC ANTIBODY TARGETING HLA-DQ2.5-GLUTEN PEPTIDES POTENTLY BLOCKS GLUTEN-SPECIFIC T CELLS INDUCED BY GLUTEN INGESTION IN PATIENTS WITH CELIAC DISEASE

被引：0
|
作者：
Hardy, Melinda Y.
Henneken, Lee
Russell, Amy
Mizoroki, Akihiko
Ozono, Yui
Okura, Yuu
Murakami, Yosuke
Kobayashi, Shinta
Tye-Din, Jason A.
机构：
来源：
GASTROENTEROLOGY | 2023年 / 164卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
18
引用
收藏
页码：S6 / S6
页数：1
相关论文
共 50 条
  • [31] LACK OF PROLIFERATIVE RESPONSE BY GLUTEN-SPECIFIC T-CELLS IN THE BLOOD AND GUT OF PATIENTS WITH DERMATITIS-HERPETIFORMIS
    BAKER, BS
    GARIOCH, JJ
    BOKTH, S
    THOMAS, H
    WALKER, MM
    LEONARD, JN
    FRY, L
    JOURNAL OF AUTOIMMUNITY, 1995, 8 (04) : 561 - 574
  • [32] γδ plus T-Cells Is a Useful Biomarker for the Differential Diagnosis between Celiac Disease and Non-Celiac Gluten Sensitivity in Patients under Gluten Free Diet
    Martin-Cardona, Albert
    Carrasco, Anna
    Arau, Beatriz
    Vidal, Judith
    Tristan, Eva
    Ferrer, Carme
    Gonzalez-Puglia, Gerardo
    Pallares, Natalia
    Tebe, Cristian
    Farrais, Sergio
    Nunez, Concepcion
    Fernandez-Banares, Fernando
    Esteve, Maria
    NUTRIENTS, 2024, 16 (14)
  • [33] Modulation of Gluten-Induced Duodenal Mucosal Injury in Celiac Disease: Results of a Randomized Controlled Phase 2 Clinical Trial of Oral Administered Gluten-Specific Proteases in Seronegative Celiac Disease Patients (Clinicaltrials.Gov Nct01255696)
    Adelman, Daniel
    Lahdeaho, Marja-leena
    Kaukinen, Katri
    Laurila, Kaija
    Marcantonio, Annette
    Maeki, Markku
    GASTROENTEROLOGY, 2012, 142 (05) : S277 - S277
  • [34] A comprehensive bioinformatic and functional screen of wheat gluten T-cell epitopes in Hla-Dq2 celiac disease in vivo
    Tye-Din, JA
    Beissbarth, T
    Anderson, RP
    GASTROENTEROLOGY, 2005, 128 (04) : A2 - A2
  • [35] Evaluation of the Frequency of HLA-DQ2/DQ8 Genes Among Patients with Celiac Disease and Those on a Gluten-Free Diet
    Kowalski, Marek K.
    Domzal-Magrowska, Danuta
    Malecka-Wojciesko, Ewa
    FOODS, 2025, 14 (02)
  • [36] HLA-DQ2.5 genes associated with celiac disease risk are preferentially expressed with respect to non-predisposing HLA genes: Implication for anti-gluten T cell response
    Pisapia, Laura
    Camarca, Alessandra
    Picascia, Stefania
    Bassi, Virginia
    Barba, Pasquale
    Del Pozzo, Giovanna
    Gianfrani, Carmen
    JOURNAL OF AUTOIMMUNITY, 2016, 70 : 63 - 72
  • [37] A WHOLE BLOOD INTERLEUKIN-2 RELEASE ASSAY OFFERS HIGHER SENSITIVITY TO DETECT GLUTEN-SPECIFIC CD4+T CELLS THAN INTERFERON-γ ELISPOT IN CELIAC DISEASE AND ACCURATELY REFLECTS GLUTEN PEPTIDE IMMUNOGENICITY
    Moscatelli, Olivia
    Russell, Amy
    Henneken, Lee
    Fothergill, Linda
    Bryant, Vanessa
    Tye-Din, Jason A.
    GASTROENTEROLOGY, 2024, 166 (05) : S195 - S195
  • [38] GLUTEN SPECIFIC, HLA-DQ RESTRICTED T-CELLS FROM CELIAC MUCOSA PRODUCE CYTOKINES WITH THL OR THO PROFILE DOMINATED BY INTERFERON-GAMMA
    NILSEN, EM
    LUNDIN, KEA
    KRAJCI, P
    SCOTT, H
    SOLLID, LM
    BRANDTZAEG, P
    GUT, 1995, 37 (06) : 766 - 776
  • [39] T-CELLS FROM THE PERIPHERAL-BLOOD OF CELIAC-DISEASE PATIENTS RECOGNIZE GLUTEN ANTIGENS WHEN PRESENTED BY HLA-DR, HLA-DQ, OR HLA-DP MOLECULES
    GJERTSEN, HA
    SOLLID, LM
    EK, J
    THORSBY, E
    LUNDIN, KEA
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1994, 39 (06) : 567 - 574
  • [40] GLUTEN-SPECIFIC CD4+T CELL DETECTION USING A WHOLE BLOOD INTERLEUKIN-2 RELEASE ASSAY IS SENSITIVE AND SPECIFIC FOR CELIAC DISEASE
    Moscatelli, Olivia
    Russell, Amy
    Henneken, Lee
    Fothergill, Linda
    Bryant, Vanessa
    Tye-Din, Jason A.
    GASTROENTEROLOGY, 2024, 166 (05) : S102 - S102
12345