Evaluation of the Antioxidant Moringa Oleifera Lam Extracts and Anti-Inflammatory Activities of and Determination of Their Active Components

被引:0
|
作者
Ahmed, Sundus Hameed [1 ]
Hassan, Hadeel Esam [1 ]
Mahdi, Ferial Majed [2 ]
机构
[1] Mustansiriyah Univ, Coll Sci, Biol Dept, Baghdad, Iraq
[2] Minist Ind & Minerals, Vet Med Dept, Ind Res & Dev, Baghdad, Iraq
来源
EGYPTIAN JOURNAL OF CHEMISTRY | 2023年 / 66卷 / 07期
关键词
Antioxidant; Moringa oleifera; TPC; Protein denaturation; FTIR; RBCs membrane stabilization;
D O I
10.21608/EJCHEM.2022.147344.6387
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
:Background: Natural products are attracting the attention of researchers due to their widespread use in pharmaceutical industries. Moringa oleifera is one of these plants with bioactivity and is used as an .antioxidant. :Objective: The current research was conducted to assess the anti-inflammatory and antioxidant efficacies of various Moringa leaf extracts and determine their active componen.ts. Materials and Methods: Different solvents (cold water, hot water, 70% ethanol, cold ethanol, and hot ethanol) were utilized to extract .M. oleif. era. The extracts were then analyzed with FTIR to determine the percentage of active compounds in each extrac .t. Stabilization of the red blood cell membrane, denaturation protein inhibition, and antioxidant potential of the extracts were .determined. Results: The FTIR analysis revealed the active components in the various extracts to be phenol compounds, as evidenced by a specific peak in certain .regions. The hot ethanolic extract was found to have the highest amount of bioactive compound (.89.33%) compared to other .extracts. Also, the same extract had the highest activity in stabilizing red blood cells, protein inhibition, as well as radical scavengi.ng. Conclusion: The findings of this investigation indicate that the hot ethanolic extract of .M. oleifera is more effective in all the test activities compared to the other extracts.
引用
收藏
页码:479 / 486
页数:8
相关论文
共 50 条
  • [31] Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract in rats: highlighting the antioxidant, anti-inflammatory, and anti-apoptotic activities
    Mohamed M. Abdel-Daim
    Saad Alkahtani
    Rafa Almeer
    Gadah Albasher
    Environmental Science and Pollution Research, 2020, 27 : 33723 - 33731
  • [32] Pharmacological Evaluation of Moringa oleifera Seeds Extract for Anti-Inflammatory Effects in a Mouse Model
    Dauda, Anas
    Usman, Abba Mus'ab
    Tahir, Albashir
    Muhammad, Ahmad Muslim
    Yunusa, Suleiman
    Kura, Aminu Umar
    ADVANCES IN PHARMACOLOGY AND PHARMACY, 2024, 12 (01) : 66 - 70
  • [33] Identification of β-Sitosterol as in Vitro Anti-Inflammatory Constituent in Moringa oleifera
    Liao, Pei-Chun
    Lai, Ming-Hoang
    Hsu, Kuang-Ping
    Kuo, Yueh-Hsiung
    Chen, Jie
    Tsai, Ming-Chih
    Li, Chun-Xiang
    Yin, Xi-Jiang
    Jeyashoke, Narumon
    Chao, Louis Kuo-Ping
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 66 (41) : 10748 - 10759
  • [34] Anti-inflammatory effects of Morninga oleifera lam extract in rats
    Georgewill OA
    Georgewill UO
    Nwankwoala RNP
    Asian Pacific Journal of Tropical Medicine, 2010, 3 (02) : 133 - 135
  • [35] Antioxidant and Anti-Inflammatory Activities ofKigelia africana(Lam.) Benth.
    Nabatanzi, Alice
    Nkadimeng, Sanah M.
    Lall, Namrita
    Kabasa, John D.
    Mcgaw, Lyndy J.
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2020, 2020
  • [36] Anti-inflammatory effects of Morninga oleifera lam extract in rats
    Georgewill, O. A.
    Georgewill, U. O.
    Nwankwoala, R. N. P.
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2010, 3 (02) : 133 - 135
  • [37] Assessment of the Antioxidant Effects of Moringa oleifera Lam. Extracts in Fish Oil during Storage
    Nascimento, Jaqueline A.
    Magnani, Marciane
    Sousa, Janaina M. B.
    Araujo, Kassandra L. G. V.
    Epaminondas, Poliana S.
    Souza, Alline S.
    Souza, Antonia L.
    Silva, M. C. D.
    Souza, Antonio G.
    JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2016, 40 (01) : 29 - 36
  • [38] Evaluation of the Polyphenol Content and Antioxidant Properties of Methanol Extracts of the Leaves, Stem, and Root Barks of Moringa oleifera Lam.
    Atawodi, Sunday E.
    Atawodi, Joy C.
    Idakwo, Gabriel A.
    Pfundstein, Beate
    Haubner, Roswitha
    Wurtele, Gerd
    Bartsch, Helmut
    Owen, Robert W.
    JOURNAL OF MEDICINAL FOOD, 2010, 13 (03) : 710 - 716
  • [39] Moringa oleifera Lam.: a comprehensive review on active components, health benefits and application
    Su, Xinyue
    Lu, Guanzheng
    Ye, Liang
    Shi, Ruyu
    Zhu, Maomao
    Yu, Xinming
    Li, Zhiyong
    Jia, Xiaobin
    Feng, Liang
    RSC ADVANCES, 2023, 13 (35) : 24353 - 24384
  • [40] Evaluation of extracts of Moringa oleifera Lam seeds obtained with NaCl and their effects on water treatment
    Madrona, Grasiele Scaramal
    Branco, Ivanise Guilherme
    Seolin, Vanessa Jurca
    Alves Filho, Benicio de Abreu
    Fagundes-Klen, Marcia Regina
    Bergamasco, Rosangela
    ACTA SCIENTIARUM-TECHNOLOGY, 2012, 34 (03) : 289 - 293