Antioxidant;
Moringa oleifera;
TPC;
Protein denaturation;
FTIR;
RBCs membrane stabilization;
D O I:
10.21608/EJCHEM.2022.147344.6387
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
:Background: Natural products are attracting the attention of researchers due to their widespread use in pharmaceutical industries. Moringa oleifera is one of these plants with bioactivity and is used as an .antioxidant. :Objective: The current research was conducted to assess the anti-inflammatory and antioxidant efficacies of various Moringa leaf extracts and determine their active componen.ts. Materials and Methods: Different solvents (cold water, hot water, 70% ethanol, cold ethanol, and hot ethanol) were utilized to extract .M. oleif. era. The extracts were then analyzed with FTIR to determine the percentage of active compounds in each extrac .t. Stabilization of the red blood cell membrane, denaturation protein inhibition, and antioxidant potential of the extracts were .determined. Results: The FTIR analysis revealed the active components in the various extracts to be phenol compounds, as evidenced by a specific peak in certain .regions. The hot ethanolic extract was found to have the highest amount of bioactive compound (.89.33%) compared to other .extracts. Also, the same extract had the highest activity in stabilizing red blood cells, protein inhibition, as well as radical scavengi.ng. Conclusion: The findings of this investigation indicate that the hot ethanolic extract of .M. oleifera is more effective in all the test activities compared to the other extracts.
机构:
Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
Grad Univ Chinese Acad Sci, Beijing 100049, Peoples R ChinaChinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
Xu, Yong-Bing
Chen, Gui-Lin
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Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
Chinese Acad Sci, Sino African Joint Res Ctr, Wuhan 430074, Hubei, Peoples R ChinaChinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
Chen, Gui-Lin
Guo, Ming-Quan
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Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
Chinese Acad Sci, Sino African Joint Res Ctr, Wuhan 430074, Hubei, Peoples R ChinaChinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China
机构:
City Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst GEBRI, Prot Res Dept, Alexandria 21934, Egypt
City Sci Res & Technol Applicat SRTA City, Pharmaceut & Fermentat Ind Dev Ctr, Alexandria, Egypt
Pharos Univ Alexandria, Alexandria, EgyptCity Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst GEBRI, Prot Res Dept, Alexandria 21934, Egypt
El-Fakharany, Esmail M.
Elsharkawy, Wafaa B.
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机构:
Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities Studies, Phys Dept, Alkharj, Saudi ArabiaCity Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst GEBRI, Prot Res Dept, Alexandria 21934, Egypt
Elsharkawy, Wafaa B.
El-Maradny, Yousra A.
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City Sci Res & Technol Applicat SRTA City, Pharmaceut & Fermentat Ind Dev Ctr, Alexandria, Egypt
Arab Acad Sci Technol & Maritime Transport AASTMT, Fac Pharm, Microbiol & Immunol, El Alamein, EgyptCity Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst GEBRI, Prot Res Dept, Alexandria 21934, Egypt
El-Maradny, Yousra A.
El-Gendi, Hamada
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City Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst, Bioproc Dev Dept, Alexandria, EgyptCity Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst GEBRI, Prot Res Dept, Alexandria 21934, Egypt
机构:
Univ Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
Sulaiman, M. R.
Zakaria, Z. A.
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Univ Teknol MARA, Fac Pharm, Shah Alam, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
Zakaria, Z. A.
Bujarimin, A. S.
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Univ Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
Bujarimin, A. S.
Somchit, M. N.
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Univ Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
Somchit, M. N.
Israf, D. A.
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Univ Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
Israf, D. A.
Moin, S.
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Univ Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, MalaysiaUniv Putra Malaysia, Dept Biomed Sci, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
机构:
Aligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, IndiaAligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, India
Fayazuddin, Mohd
Ahmad, Farida
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Aligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, IndiaAligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, India
Ahmad, Farida
Kumar, Anil
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Aligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, IndiaAligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, India
Kumar, Anil
Yunus, S. M.
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机构:
Aligarh Muslim Univ, JN Med Coll, Dept Anat, Aligarh, Uttar Pradesh, IndiaAligarh Muslim Univ, JN Med Coll, Dept Pharmacol, Aligarh, Uttar Pradesh, India