The effects and underlying mechanism of extracorporeal shockwave therapy on fracture healing

被引：7

作者：

Lv, Fuxian ^{[1
]}

Li, Zhenlan ^{[1
]}

Jing, Yuling ^{[1
]}

Sun, Liyuan ^{[1
]}

Li, Zhiwei ^{[1
]}

Duan, Haoyang ^{[1
]}

机构：

[1] First Hosp Jilin Univ, Dept Rehabil Med, Changchun, Peoples R China

来源：

FRONTIERS IN ENDOCRINOLOGY | 2023年 / 14卷

关键词：

extracorporeal shockwave therapy; fracture; osteogenesis; growth factor; review; MESENCHYMAL STEM-CELLS; BINDING-FACTOR-BETA; GROWTH-FACTOR-I; WAVE THERAPY; BONE REPAIR; CBF-BETA; EXPRESSION; DIFFERENTIATION; VEGF; TGF-BETA-1;

D O I：

10.3389/fendo.2023.1188297

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical efficacy of ESWT in treating bone non union has been widely recognized, but the biological mechanism of ESWT promoting bone non union healing is still unclear. ESWT can make old callus micro fracture through mechanical conduction, form subperiosteal hematoma, promote the release of bioactive factors, reactivate the fracture healing mechanism, rebalance the activities of osteoblasts and osteoclast, promote the angiogenesis of fracture site, and accelerate the healing of bone nonunion.Over recent years, great efforts have been made by both scientists and clinicians to explore the underlying mechanism behind the healing effect of ESWT on bone fractures. In this review, we introduced the growth factors during osteogenesis induced by ESWT hoping to provide new insights in the clinical use of ESWT.

引用

页数：7

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