The effects and underlying mechanism of extracorporeal shockwave therapy on fracture healing

被引：7
|
作者：
Lv, Fuxian [1 ]
Li, Zhenlan [1 ]
Jing, Yuling [1 ]
Sun, Liyuan [1 ]
Li, Zhiwei [1 ]
Duan, Haoyang [1 ]
机构：
[1] First Hosp Jilin Univ, Dept Rehabil Med, Changchun, Peoples R China
来源：
FRONTIERS IN ENDOCRINOLOGY | 2023年 / 14卷
关键词：
extracorporeal shockwave therapy; fracture; osteogenesis; growth factor; review; MESENCHYMAL STEM-CELLS; BINDING-FACTOR-BETA; GROWTH-FACTOR-I; WAVE THERAPY; BONE REPAIR; CBF-BETA; EXPRESSION; DIFFERENTIATION; VEGF; TGF-BETA-1;
D O I：
10.3389/fendo.2023.1188297
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The clinical efficacy of ESWT in treating bone non union has been widely recognized, but the biological mechanism of ESWT promoting bone non union healing is still unclear. ESWT can make old callus micro fracture through mechanical conduction, form subperiosteal hematoma, promote the release of bioactive factors, reactivate the fracture healing mechanism, rebalance the activities of osteoblasts and osteoclast, promote the angiogenesis of fracture site, and accelerate the healing of bone nonunion.Over recent years, great efforts have been made by both scientists and clinicians to explore the underlying mechanism behind the healing effect of ESWT on bone fractures. In this review, we introduced the growth factors during osteogenesis induced by ESWT hoping to provide new insights in the clinical use of ESWT.
引用
收藏
页数：7
相关论文
共 50 条
  • [1] Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy
    Haffner, Nicolas
    Antonic, Vlado
    Smolen, Daniel
    Slezak, Paul
    Schaden, Wolfgang
    Mittermayr, Rainer
    Stojadinovic, Alexander
    INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2016, 47 (07): : 1506 - 1513
  • [2] Biological effects of extracorporeal shockwave in bone healing: a study in rabbits
    Wang, Ching-Jen
    Wang, Feng-Sheng
    Yang, Kuender D.
    ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 2008, 128 (08) : 879 - 884
  • [3] Biological effects of extracorporeal shockwave in bone healing: a study in rabbits
    Ching-Jen Wang
    Feng-Sheng Wang
    Kuender D. Yang
    Archives of Orthopaedic and Trauma Surgery, 2008, 128
  • [4] Low-energy extracorporeal shockwave therapy (ESWT) improves metaphyseal fracture healing in an osteoporotic rat model
    Mackert, Gina A.
    Schulte, Matthias
    Hirche, Christoph
    Kotsougiani, Dimitra
    Vogelpohl, Julian
    Hoener, Bernd
    Fiebig, Teresa
    Kirschner, Stefanie
    Brockmann, Marc A.
    Lehnhardt, Marcus
    Kneser, Ulrich
    Harhaus, Leila
    PLOS ONE, 2017, 12 (12):
  • [5] Extracorporeal shockwave therapy: A systematic review of its use in fracture management
    Petrisor, B. A.
    Lisson, Selene
    Sprague, Sheila
    INDIAN JOURNAL OF ORTHOPAEDICS, 2009, 43 (02) : 161 - 167
  • [6] A review of the cellular and molecular effects of extracorporeal shockwave therapy
    Chamberlain, Georgina A.
    Colborne, G. Robert
    VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY, 2016, 29 (02) : 99 - 107
  • [7] The Efficacy of Extracorporeal Shockwave Therapy Compared with Compression Therapy in Healing Venous Leg Ulcers
    Dolibog, Pawel T.
    Dolibog, Patrycja
    Bergler-Czop, Beata
    Grzegorczyn, Slawomir
    Chmielewska, Daria
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (07)
  • [8] Extracorporeal shockwave therapy - A review
    Chung, B
    Wiley, JP
    SPORTS MEDICINE, 2002, 32 (13) : 851 - 865
  • [9] The effects of extracorporeal shockwave therapy on matrix metalloprotease activity in tendinopathy
    Waugh, Charlie
    Jones, Eleanor
    Riley, Graham
    Langberg, Henning
    Morrissey, Dylan
    Screen, Hazel
    FASEB JOURNAL, 2014, 28 (01):
  • [10] Dosage effects of extracorporeal shockwave therapy in early hip necrosis
    Wang, Ching-Jen
    Huang, Chung-Cheng
    Yip, Hon-Kan
    Yang, Ya-Ju
    INTERNATIONAL JOURNAL OF SURGERY, 2016, 35 : 179 - 186
12345