Imidazole-carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

被引：12
|
作者：
Pham, Thanh Chung [1 ]
Lee, Dong Joon [2 ]
Kim, Do Hun [3 ]
Yoon, Juyoung [4 ]
Lam, Tran Dai [1 ]
Kim, Hwan Myung [2 ,5 ]
Lee, Songyi [3 ,6 ]
机构：
[1] Vietnam Acad Sci & Technol, Inst Trop Technol, 18 Hoang Quoc Viet, Hanoi, Vietnam
[2] Ajou Univ, Dept Chem, Suwon 16400, South Korea
[3] Pukyong Natl Univ, Ind Convergence Bion Engn 4 0, Pusan 48513, South Korea
[4] Ewha Womans Univ, Dept Chem & Nanosci, Seoul 03760, South Korea
[5] Ajou Univ, Dept Energy Syst Res, Suwon 16499, South Korea
[6] Pukyong Natl Univ, Dept Chem, Pusan 48513, South Korea
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 30期
基金：
新加坡国家研究基金会;
关键词：
ATOM-FREE PHOTOSENSITIZERS; MOLECULAR DESIGN; CANCER; ABSORPTION;
D O I：
10.1039/d3cc00108c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A heavy-atom-free photosensitizer (CI) based on an imidazole-carbazole conjugate exhibited strong fluorescence emission and ROS generation via both type I and II mechanisms. In particular, CI showed efficient photodynamic therapy and fluorescence bioimaging under two-photon (TP) excitation (740 nm) toward HeLa cells with negligible dark toxicity.
引用
收藏
页码：4503 / 4506
页数：4
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