Adverse Effects Under Th2 Biologics (Dupilumab and Tezepelumab) in a Patient with Severe Asthma and Atopic Dermatitis

被引：1

作者：

Suhling, Hendrik ^{[1
]}

Hinze, Christopher Alexander ^{[1
]}

Welte, Tobias ^{[1
]}

Werfel, Thomas ^{[2
]}

Traidl, Stephan ^{[2
]}

机构：

[1] Hannover Med Sch, Dept Resp Med & Infect Dis, Hannover, Germany

[2] Hannover Med Sch, Dept Dermatol & Allergy, Hannover, Germany

来源：

RESPIRATION | 2023年 / 102卷 / 12期

关键词：

Severe asthma; Dupilumab; Tezepelumab; Side effects;

D O I：

10.1159/000534924

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Introduction: This is the first report of a patient with severe asthma and atopic dermatitis that developed local perioral skin infection which onset coincided with the patient's treatment with dupilumab (candida albicans) and later with tezepelumab (microscopic detection of yeast). Case Presentation: Besides moderate headache, macular exanthema was found after administration of tezepelumab, which was subsequently accompanied by a worsening of symptoms upon reexposure to the treatment. Both sensations needed multidisciplinary treatment and both antibody therapies were stopped.

引用

页码：1016 / 1019

页数：4

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