Green synthesis of copper nanoparticles from Nigella sativa seed extract and evaluation of their antibacterial and antiobesity activity

被引：26

作者：

Kumar, Mukul ^{[1
]}

Kaushik, Deepika ^{[2
]}

Kumar, Ashwani ^{[3
]}

Gupta, Prerna ^{[1
]}

Proestos, Charalampos ^{[4
]}

Oz, Emel ^{[5
]}

Orhan, Elif ^{[6
]}

Kaur, Jasjit ^{[1
]}

Khan, Mohammad Rizwan ^{[7
]}

Elobeid, Tahra ^{[8
]}

Bordiga, Matteo ^{[9
]}

Oz, Fatih ^{[5
]}

机构：

[1] Lovely Profess Univ, Dept Food Technol & Nutr, Phagwara 144411, India

[2] Shoolini Univ, Fac Appl Sci & Biotechnol, Dept Biotechnol, Solan 173229, India

[3] Rani Lakshmi Bai Cent Agr Univ, Coll Hort & Forestry, Dept Postharvest Technol, Jhansi 284003, India

[4] Natl & Kapodistrian Univ Athens Zographou, Dept Chem, Food Chem Lab, Athens 15784, Greece

[5] Ataturk Univ, Fac Agr, Dept Food Engn, TR-25240 Erzurum, Turkiye

[6] Gazi Univ, Dept Phys, TR-06500 Ankara, Turkiye

[7] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia

[8] Qatar Univ, Coll Hlth Sci, Human Nutr Dept, QU Hlth, Doha 2713, Qatar

[9] Univ Piemonte Orientale, Dept Pharmaceut Sci, Largo Donegani 2, I-28100 Novara, Italy

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY | 2023年 / 58卷 / 06期

关键词：

Amylase inhibition assay; antibacterial activity; black cumin; copper nanoparticles (CuNPs); lipase inhibition assay; Nigella sativa; SILVER NANOPARTICLES; METALLIC NANOPARTICLES; PLANTS;

D O I：

10.1111/ijfs.16359

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

In this study, the copper nanoparticles were synthesized using various concentrations (5%, 6 %, 8%, and 10%) of Nigella sativa seed extracts, and their antibacterial and antiobesity effect was evaluated. The optimum particle size (98.23 nm) of nanoparticles was obtained at an extract concentration of 8%. FTIR results confirmed the functional groups responsible for copper ion reduction, The synthesized nanoparticles exhibited high antibacterial activity against Pseudomonas aeruginosa and Escherichia coli having inhibition zone of 25 mm and 24 mm, respectively. Significantly (P < 0.005) percent lipase and amylase inhibition assay of copper nanoparticles confirmed their antiobesity activities.

引用

页码：2883 / 2892

页数：10

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