Rhodium(III)-Catalyzed Divergent C-H Functionalization of N-Aryl Amidines with Iodonium Ylides: Access to Carbazolones and Zwitterionic Salts

被引：16

作者：

Ren, Jie

Yang, Liu

Pi, Chao

Cui, Xiuling ^{[1
]}

Wu, Yangjie ^{[1
]}

机构：

[1] Zhengzhou Univ, Green Catalysis Ctr, Key Lab Appl Chem Henan Univ, Henan Key Lab Chem Biol & Organ Chem, Zhengzhou 450052, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2023年 / 365卷 / 11期

关键词：

C-H bond functionalization; Hypervalent iodine-(III) ylides; Intramolecular proton transfer; Carbazolones; Zwitterionic salts; RAPID ACCESS; ACTIVATION; PHENOXYACETAMIDES; ANNULATION; RH(III); INDOLE; BOND;

D O I：

10.1002/adsc.202201390

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We described an Rhodium(III)-catalyzed divergent C-H bond functionalization of N-aryl amidines with iodonium ylides. Carbazolones and zwitterionic salts were diversely constructed through intermolecular annulation and intramolecular proton transfer under the different reaction conditions. This protocol is operationally simple and tolerates a variety of functional groups. The efficient post-modification of pharmaceutical molecules demonstrates its practicability.

引用

页码：1817 / 1823

页数：7

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