Development of Triple-negative breast cancer (TNBC) syngeneic models and TROP2-directed antibody-drug conjugate (ADC) surrogate to model therapeutic combinations

被引:0
|
作者
Chou, Chih-Chien
Kardos, Jordan
Yang, Becky
Orf, Jessica
Dave, Rutwij
Lai, Yurong
Lee, Chingwei V.
Papalia, Giuseppe A.
Boyd, Kelli
Diehl, Lauri
Scholler, Nathalie
机构
关键词
D O I
10.1158/1538-7445.SABCS22-P4-07-12
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P4-07-12
引用
收藏
页数:3
相关论文
共 50 条
  • [31] Breaking barriers in triple negative breast cancer (TNBC) - Unleashing the power of antibody-drug conjugates (ADCs)
    Dri, Arianna
    Arpino, Grazia
    Bianchini, Giampaolo
    Curigliano, Giuseppe
    Danesi, Romano
    De Laurentiis, Michelino
    Del Mastro, Lucia
    Fabi, Alessandra
    Generali, Daniele
    Gennari, Alessandra
    Guarneri, Valentina
    Santini, Daniele
    Simoncini, Edda
    Zamagni, Claudio
    Puglisi, Fabio
    CANCER TREATMENT REVIEWS, 2024, 123
  • [32] Therapy of relapsed/refractory metastatic triple-negative breast cancer (mTNBC) with an anti-Trop-2-SN-38 antibody-drug conjugate (ADC), sacituzumab govitecan (IMMU-132): Phase II results.
    Bardia, Aditya
    Diamond, Jennifer Robinson
    Messersmith, Wells A.
    Mayer, Ingrid A.
    Isakoff, Steven J.
    Abramson, Vandana Gupta
    Berlin, Jordan
    Starodub, Alexander
    O'Shaughnessy, Joyce
    Kalinsky, Kevin
    Moroose, Rebecca L.
    Shah, Nikita C.
    Juric, Dejan
    Shapiro, Geoffrey
    Guarino, Michael J.
    Ocean, Allyson J.
    Wilhelm, Francois
    Sharkey, Robert M.
    Goldenberg, David M.
    Vahdat, Linda T.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (18)
  • [34] Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
    Cheung, Anthony
    Chenoweth, Alicia M.
    Johansson, Annelie
    Laddach, Roman
    Guppy, Naomi
    Trendell, Jennifer
    Esapa, Benjamina
    Mavousian, Antranik
    Navarro-Llinas, Blanca
    Haider, Syed
    Romero-Clavijo, Pablo
    Hoffmann, Ricarda M.
    Andriollo, Paolo
    Rahman, Khondaker M.
    Jackson, Paul
    Tsoka, Sophia
    Irshad, Sheeba
    Roxanis, Ioannis
    Grigoriadis, Anita
    Thurston, David E.
    Lord, Christopher J.
    Tutt, Andrew N. J.
    Karagiannis, Sophia N.
    CLINICAL CANCER RESEARCH, 2024, 30 (15) : 3298 - 3315
  • [35] Discovery of BCG033, a novel anti-PTK7 x TROP2 bispecific antibody-drug conjugate with promising efficacy against triple-negative breast cancer
    Yao, Sufei
    Shang, Chengzhang
    An, Gao
    Zhang, Ellen
    Lin, Qingcong
    Yang, Yi
    CANCER RESEARCH, 2023, 83 (08)
  • [36] Novel Therapies for Metastatic Triple-Negative Breast Cancer: Spotlight on Immunotherapy and Antibody-Drug Conjugates
    Nagayama, Aiko
    Vidula, Neelima
    Bardia, Aditya
    ONCOLOGY-NEW YORK, 2021, 35 (05): : 249 - 255
  • [37] Advances in antibody-drug conjugates in the treatment of advanced triple-negative breast cancer: a narrative review
    Jiang, Kuikui
    Wang, Shusen
    TRANSLATIONAL BREAST CANCER RESEARCH, 2025, 6
  • [38] Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancer
    Gough, Madeline
    Kwah, Kayden
    He, Yaowu
    Snell, Cameron Edward
    Hooper, John D.
    Kryza, Thomas
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [39] ESG401, a novel Trop2 antibody-drug conjugate (ADC), and its efficacy evidence in HER2-negative metastatic breast cancer with brain metastases
    Ma, F.
    Qiu, F.
    Tong, Z.
    Wang, J.
    Shi, Y.
    Li, L.
    Yu, G.
    Shi, H.
    Wu, X.
    Liu, A.
    Zhang, Y.
    Wang, H.
    Cheng, Y.
    Yang, H.
    Li, H.
    Chang, J.
    Zhou, Q.
    ANNALS OF ONCOLOGY, 2024, 35 : S359 - S359
  • [40] Excellent effects and possible mechanisms of action of a new antibody-drug conjugate against EGFR-positive triple-negative breast cancer
    Zhou, Dan-Dan
    Bai, Wei-Qi
    Zhai, Xiao-Tian
    Sun, Li-Ping
    Zhen, Yong-Su
    Li, Zhuo-Rong
    Miao, Qing-Fang
    MILITARY MEDICAL RESEARCH, 2021, 8 (01)