Molecular docking and antioxidant activity studies of imidodithiocarbonate derivatives containing pyrimidine

被引：0

作者：

Korkusuz, Elif ^{[1
]}

Sert, Yusuf ^{[2
]}

Selvi, Emine Kilickaya ^{[1
]}

Aydin, Hava ^{[3
]}

Koca, Irfan ^{[4
]}

Yildirim, Ismail ^{[3
]}

机构：

[1] Kayseri Univ, Mustafa Cikrikcioglu Vocat Coll, TR-38039 Kayseri, Turkiye

[2] Yozgat Bozok Univ, Fac Arts & Sci, Dept Phys, TR-66900 Yozgat, Turkiye

[3] Erciyes Univ, Fac Sci, Dept Chem, TR-38039 Kayseri, Turkiye

[4] Yozgat Bozok Univ, Fac Arts & Sci, Dept Chem, TR-66900 Yozgat, Turkiye

来源：

ORGANIC COMMUNICATIONS | 2023年 / 16卷 / 01期

关键词：

Pyrimidine; imidodithiocarbonate; molecular docking; antioxidant activity; FRONTIER ORBITALS; OXALYL COMPOUNDS;

D O I：

10.25135/acg.oc.143.2212.2658

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Imidodithiocarbonate derivatives containing pyrimidine ring, potentially functional molecules were synthesized and characterized. FTIR, 1H NMR and 13C NMR spectroscopy and elemental analysis methods were used for characterization. The obtained compounds were screened for their antioxidant capacity using DPPH (1,1diphenyl-2-picrylhydraziyl) free radical-scaving and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonicacid) assays. The possible interactions between the molecular docking calculations of the synthesized imidodithiocarbonate derivatives and their binding potentials to the active sites of target enzymes.

引用

页码：1 / 10

页数：10

共 50 条

[31] Synthesis, docking studies and antioxidant activity of some chalcone and aurone derivatives
Tamanna Narsinghani
Mukesh C. Sharma
Sakshi Bhargav
Medicinal Chemistry Research, 2013, 22 : 4059 - 4068
[32] Antioxidant and tyrosinase docking studies of heterocyclic sulfide derivatives containing a thymol moiety
Havasi, Mia H.
Ressler, Andrew J.
Parks, Eden L.
Cocolas, Alexander H.
Weaver, Ashton
Seeram, Navindra P.
Henry, Geneive E.
INORGANICA CHIMICA ACTA, 2020, 505 (505)
[33] Synthesis and molecular docking of pyrimidine derivatives as antibacterial agents
Elumalai, Karthikeyan
Shanmugam, Anandakumar
Devaraji, Mahalakshmi
Srinivasan, Sivaneswari
CARBON RESOURCES CONVERSION, 2024, 7 (03)
[34] Synthesis, Characterization, Antimicrobial Activity Screening, and Molecular Docking Study of Pyrimidine Carbonitrile Derivatives
Radhika Bhat
Noor Shahina Begum
Russian Journal of Organic Chemistry, 2021, 57 : 1352 - 1360
[35] Design, synthesis, molecular docking and antimicrobial evaluation of benzoylurea derivatives containing difluoromethyl (trifluoromethyl) pyrimidine
Wu, Wenneng
An, Jiansong
Lan, Wenjun
Chen, Haijiang
Fei, Qiang
Xu, Su
Yin, Rongxiu
Yang, Lin-Lin
Yang, Song
PEST MANAGEMENT SCIENCE, 2025, 81 (04) : 1804 - 1816
[36] Synthesis, Characterization, Antimicrobial Activity Screening, and Molecular Docking Study of Pyrimidine Carbonitrile Derivatives
Bhat, Radhika
Begum, Noor Shahina
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 57 (08) : 1352 - 1360
[37] Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking
Veeraswamy, B.
Madhu, D.
Dev, G. Jitender
Poornachandra, Y.
Kumar, G. Shravan
Kumar, C. Ganesh
Narsaiah, B.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (09) : 1670 - 1675
[38] Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives
Giles, D.
Roopa, Karki
Sheeba, F. R.
Gurubasavarajaswamy, P. M.
Divakar, Goli
Vidhya, Thomas
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 58 : 478 - 484
[39] Synthesis of Chalcone Derivatives and Studies on Their Inhibitory Activity and Molecular Docking
Xiao, Tingting
Cheng, Wei
Qian, Weifeng
Zhang, Tingting
Lu, Tong
Gao, Yang
Tang, Xiaorong
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 40 (06) : 1704 - 1715
[40] SYNTHESIS AND ANTIOXIDANT ACTIVITY OF NOVEL PYRIMIDINE DERIVATIVES
Kumar, Hemanth
Revanasiddappa, B. C.
HETEROCYCLIC LETTERS, 2020, 10 (01): : 57 - 62

← 1 2 3 4 5 →