Reduction of mycophenolate mofetil dosage to limit prolonged viral shedding in solid organ transplant recipients with COVID-19: Two case reports

被引：0
|
作者：
Murai, Yushi [1 ,4 ]
Sakao, Seiichiro [1 ]
Kure, Fujihiro [1 ]
Kawasaki, Takeshi [1 ]
Maruyama, Michihiro [2 ]
Suzuki, Hidemi [3 ]
Yoshino, Ichiro [3 ]
Suzuki, Takuji [1 ]
机构：
[1] Chiba Univ, Grad Sch Med, Dept Respirol, Chiba 2608670, Japan
[2] Chiba Univ, Grad Sch Med, Dept Esophageal Gastro Intestinal Surg, Chiba 2608670, Japan
[3] Chiba Univ, Grad Sch Med, Dept Gen Thorac Surg, Chiba 2608670, Japan
[4] Chiba Univ, Grad Sch Med, Dept Respirol, 1 Inohana Chuo Ku, Chiba 2608670, Japan
来源：
RESPIRATORY INVESTIGATION | 2024年 / 62卷 / 01期
关键词：
COVID-19; Mycophenolic acid; Lung transplantation; Kidney transplantation; CULTURES;
D O I：
10.1016/j.resinv.2023.10.006
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Solid organ transplant (SOT) recipients with coronavirus disease-2019 (COVID-19) experience prolonged viral shedding, and they are forced to stay in the hospital because of the requirement for COVID-19 isolation. Here, we present two cases (lung and renal transplant recipients), wherein the isolation period was shortened by reducing the dosage of mycophenolate mofetil (MMF). Both patients recovered well from COVID-19 pneumonia. This case study suggests that a reduction in MMF dosage may lead to a shorter hospitalization period in SOT recipients with COVID-19.
引用
收藏
页码：98 / 101
页数：4
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