Synthesis of copper nanoparticles from the leaf extract of Psidium guajava']java L. and its antioxidant, anticancer, antifungal activities

被引:2
|
作者
Sriram, T. [1 ]
Vijayanand, S. [1 ]
Malathi, R. [1 ]
Dsouza, Vailina F. [2 ]
机构
[1] Kristu Jayanti Coll, Dept Life Sci, Bangalore 560064, Karnataka, India
[2] Univ Coll Dublin, Dept Med, Dublin, Ireland
来源
关键词
Copper nanoparticles; Psidium gua[!text type='java']java[!/text] L; Candida albicans; Anticancer activity;
D O I
10.54085/ap.2023.12.2.55
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Over the past years, the field of nanotechnology has immensely evolved. It is no longer a single industry but now has developed to become a shared collection of materials and practices as it has created a larger impact on various industries such as chemicals, electronics, agriculture, medicine and space. The usage of nanoparticles in the medical industry has gained a lot of interest lately due to their promising properties making them an excellent focus of interest. Green synthesis of copper nanoparticles has shown to be advantageous as it is highly conductive and inexpensive than silver and gold. However, the downfall is the aggregation and oxidation of copper nanoparticles. The usage and selection of a suitable stabilizer for the capping of copper nanoparticles can overcome these problems. The present study reveals copper nanoparticles synthesized from leaf extract of Psidium guajava L., displayed antifungal efficacy against the pathogen Candida albicans with a 0.5 cm zone of inhibition. The synthesized copper nanoparticle shows anticancer activity in HeLa cell lines with 1000 mu g/ml concentration of the nanoparticle. In future, the copper nanoparticles can be effective in the treatment of cancer and human pathogens.
引用
收藏
页码:446 / 451
页数:6
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