Invasive Streptococcus pneumoniae disease (IPD) remains a serious cause of morbidity and loss of life in children and adults worldwide. While pneumococcal vaccines have reduced the frequency of invasive pneumococcal disease, the emergence of invasive non-vaccine serotypes has mandated the development of novel pneumococcal vaccines to further protect against these emerging serotypes. We present a case of a non-vaccine serotype invasive pneumococcal disease-causing septic shock, meningitis, and stroke in a previously healthy and appropriately vaccinated 23-month-old male.
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Northwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL 60611 USA
Childrens Mem Hosp, Div Pediat Infect Dis, Int Adoptee Clin, Chicago, IL 60614 USANorthwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL 60611 USA
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St Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, EnglandSt Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, England
Weir, A
Lam, D
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St Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, EnglandSt Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, England
Lam, D
Wansbrough-Jones, M
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St Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, EnglandSt Georges Hosp, Sch Med, Dept Cellular & Mol Sci, Div Infect Dis, London SW17 0QT, England
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Turku Univ Hosp, Dept Pediat, Turku 20521, Finland
Univ Turku, Turku Inst Child & Youth Res, Turku, FinlandTurku Univ Hosp, Dept Pediat, Turku 20521, Finland