Ultrasensitive Electrochemical Sensor Based on Vertical Graphene for SARS-CoV-2 Protein N Detection

Monitoring and controlling infection is required in order to prevent the progression of the coronavirus severe acute respiratory syndrome 2(SARS-CoV-2). To accomplish this goal, the development and implementation of sensitive, quick and accurate diagnostic methods are essential. Electrochemical sensors have exposed large application possibilities in biological detection due to the advantages of high sensitivity, short time-consuming and specificity. Here, we report the improvement of a sensitive electrochemical sensor capable of detecting the presence of the SARS-CoV-2 virus using graphene-modified interdigitated working electrodes functionalized with antibodies targeting the SARS-CoV-2 nucleocapsid protein (N protein).