Relative leukocyte telomere length in patients with chronic alcohol addiction depending on clinical and anamnestic characteristics

被引：0
|
作者：
Kazantseva, A. V. [1 ]
Davydova, Y. D. [2 ]
Fashkhutdinova, G. G. [2 ]
Enikeeva, R. F. [2 ]
Fedorova, Y. Y. [2 ]
Gareeva, A. E. [2 ]
Asadullin, A. R. [2 ]
Mikhaylova, A. V. [2 ]
Valinurov, R. G. [3 ]
Khusnutdinova, E. K. [2 ]
机构：
[1] Russian Acad Sci, Ufa Fed Res Ctr, Separate Struct Subdiv, Inst Biochem & Genet, Moscow, Russia
[2] Ufa Univ Sci & Technol UUST, Ufa, Russia
[3] Bashkir State Med Univ, Ufa, Russia
来源：
YAKUT MEDICAL JOURNAL | 2023年 / 01期
关键词：
alcohol addiction; telomeres; cell aging; allostatic load; biomarkers; clinical and anamnestic characteristics; ASSOCIATION; CONSUMPTION;
D O I：
10.25789/YMJ.2023.81.01
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The present study aimes to examine for the hypothesis on the association of shorter relative telomere length (RTL) with chronic alcohol addiction accounting for the clinical and anamnestic characteristics. We identified statistically significant effect of age on variance in RTL in the total sample and separately in men with alcohol dependence. Among the examined clinical and anamnestic parameters, the age at onset of withdrawal syndrome negatively affected RTL.
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页码：5 / 9
页数：5
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