The role of extracellular vesicles in COPD and potential clinical value

被引：1
|
作者：
Liu, Shasha [1 ]
Tan, Xiaowu [1 ]
Liu, Sha [1 ]
机构：
[1] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Pulm & Crit Care Med, Hengyang, Hunan, Peoples R China
来源：
RESPIRATORY RESEARCH | 2024年 / 25卷 / 01期
关键词：
Extracellular vesicles; Chronic obstructive pulmonary disease; Pathogenesis; Biomarkers; Clinical application; OBSTRUCTIVE PULMONARY-DISEASE; CIRCULATING ENDOTHELIAL MICROPARTICLES; OXIDATIVE STRESS; EPITHELIAL-CELLS; CIGARETTE-SMOKE; LUNG HEALTH; CLASS-II; EXOSOMES; MICROVESICLES; SENESCENCE;
D O I：
10.1186/s12931-024-02719-z
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure that are secreted by various cells. They contain a variety of bioactive substances, which can regulate various physiological and pathological processes and are closely related to the development of diseases. Recently, EVs have emerged as a novel tool for intercellular crosstalk, which plays an essential role in COPD development. This paper reviews the role of EVs in the development of COPD and their potential clinical value, in order to provide a reference for further research on COPD.
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页数：10
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