Evaluating the Safety of HCAR19 (Now Actalycabtagene Autoleucel- Actaly-CelT), a Novel Humanized CD19-Directed Chimeric Antigen Receptor T-Cells in Pediatric, Adolescents, and Young Adults with Relapsed/ Refractory B- Acute Lymphoblastic Leukemia (ESHA) - Report of Phase-1B

被引：2

作者：

Narula, Gaurav ^{[1
]}

Keerthivasagam, Swaminathan ^{[2
]}

Jain, Hasmukh ^{[1
]}

Dhamne, Chetan ^{[2
]}

Tembhare, Prashant ^{[3
]}

Subramanian, Papagudi Ganesan ^{[3
]}

Patkar, Nikhil ^{[3
]}

Poojary, Minal ^{[4
]}

Nisar, Albeena ^{[5
]}

Pandit, Deepali ^{[6
]}

Pandit, Khushali ^{[7
]}

Karulkar, Atharva ^{[8
]}

Jaiswal, Ankesh Kumar ^{[8
]}

Khan, Aalia ^{[8
]}

Shah, Shreshtha ^{[8
,9
]}

Firfiray, Afrin ^{[8
]}

Pendhari, Juber ^{[8
]}

Asija, Sweety ^{[8
]}

Chowdury, Ambalika ^{[8
]}

Banik, Ankit ^{[8
]}

Moulik, Nirmalya Roy ^{[2
]}

Srinivasan, Shyam ^{[10
]}

Bhosle, Shilpushp ^{[11
]}

Hiregoudar, Sumathi ^{[3
]}

Ojha, Shashank ^{[3
]}

Nayak, Lingaraj ^{[3
,12
]}

Thorat, Jayshree ^{[13
]}

Bagal, Bhausaheb ^{[3
,12
]}

Sengar, Manju ^{[1
]}

Jindal, Nishant ^{[3
,12
]}

Chichra, Akanksha ^{[12
]}

Mirgh, Sumeet ^{[3
,12
]}

Gokarn, Anant ^{[3
,12
]}

Punatar, Sachin ^{[3
,12
]}

Rajadhyaksha, Sunil ^{[14
]}

Khattry, Navin ^{[3
,12
]}

Banavali, Shripad ^{[15
]}

Highfill, Steven ^{[16
]}

Shah, Nirali N. ^{[17
]}

Purwar, Rahul ^{[18
]}

机构：

[1] Homi Bhabha Natl Inst, Dept Med Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India

[2] Homi Bhabha Natl Inst, Dept Pediat Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India

[3] Homi Bhabha Natl Inst, Dept Hematopathol, Tata Mem Ctr, Adv Ctr Treatment Res & Educ Canc ACTREC, Navi Mumbai, India

[4] Homi Bhabha Natl Inst, Dept Transfus Med, Tata Mem Ctr, Navi Mumbai, India

[5] ACTREC, CAR T & Cell Therapy Ctr, Tata Mem Ctr, Sci Off D, Mumbai, Maharashtra, India

[6] Tata Mem Hosp, CAR T & Cell Therapy Ctr, ACTREC, Kharghar, India

[7] Tata Mem Hosp, CAR T & Cell Therapy Ctr, ACTREC, Mumbai, Maharashtra, India

[8] Indian Inst Technol, Dept Biosci & Bioengn, Mumbai, Maharashtra, India

[9] ImmunoACT, Immunoadopt Cell Therapy Private Ltd, Mumbai, Maharashtra, India

[10] Homi Bhabha Natl Inst, Dept Pediat Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India

[11] Homi Bhabha Natl Inst, Dept Crit Care & Anaesthesiol, Tata Mem Ctr, Mumbai, Maharashtra, India

[12] Homi Bhabha Natl Inst, Dept Med Oncol, BMT Unit,Tata Mem Ctr, Adv Ctr Treatment Res & Educ Canc ACTREC, Navi Mumbai, India

[13] Homi Bhabha Natl Inst, Dept Med Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India

[14] Homi Bhabha Natl Inst, Dept Transfus Med, Tata Mem Ctr, Mumbai, Maharashtra, India

[15] Tata Mem Hosp, Dept Med Oncol, Homi Bhabha Natl Inst, Mumbai, Maharashtra, India

[16] Natl Inst Hlth, Ctr Cellular Engn, Bethesda, MD USA

[17] Natl Inst Hlth, Pediat Oncol Branch, Bethesda, MD USA

[18] Indian Inst Technol B, Dept Biosci & Bioengn, Mumbai, Maharashtra, India

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-180867

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：6

共 29 条

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Yaqing Cao
Luqiao Wang
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