Mechanisms of ADAMTS13 inhibition in iTTP

被引：0
|
作者：
Laemmle, Bernhard [1 ,2 ]
机构：
[1] Univ Bern, Bern, Switzerland
[2] Univ Med Ctr Mainz, Mainz, Germany
来源：
BLOOD | 2023年 / 141卷 / 24期
关键词：
D O I：
10.1182/blood.2023020512
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Halkidis et al(1) present an article that is a must-read for all hematologists, not just those specializing in autoimmune thrombotic thrombocytopenic purpura (iTTP). Every researcher and clinician will benefit from studying this article because it highlights that a scientific topic, no matter how well studied, may benefit from critical reexamination, performance of additional studies, and adjusting the conclusions as indicated by this process.
引用
收藏
页码：2919 / 2920
页数：2
相关论文
共 50 条
  • [41] Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels
    Ma, Qianyi
    Jacobi, Paula M.
    Emmer, Brian T.
    Kretz, Colin A.
    Ozel, Ayse Bilge
    McGee, Beth
    Kimchi-Sarfaty, Chava
    Ginsburg, David
    Li, Jun Z.
    Desch, Karl C.
    BLOOD ADVANCES, 2017, 1 (15) : 1037 - 1046
  • [42] Normalization of ADAMTS13 activity in rats with an adjusted inhibitor titer by administration of recombinant ADAMTS13
    Schiviz, Alexandra
    Plaimauer, Barbara
    Kaufmann, Stefan
    Hoebarth, Gerald
    Wolfsegger, Martin
    Muchitsch, Eva-Maria
    Turecek, Peter L.
    Scheiflinger, Friedrich
    Rottensteiner, Hanspeter
    HAEMOPHILIA, 2014, 20 : 103 - 104
  • [43] ADAMTS13 conformations and mechanism of inhibition in immune thrombotic thrombocytopenic purpura
    Halkidis, Konstantine
    Zheng, X. Long
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022, 20 (10) : 2197 - 2203
  • [44] Congenital and acquired ADAMTS13 deficiency: Two mechanisms, one patient
    Ferrari, Barbara
    Cairo, Andrea
    Pontiggia, Silvia
    Mancini, Ilaria
    Masini, Luciano
    Peyvandi, Flora
    JOURNAL OF CLINICAL APHERESIS, 2015, 30 (04) : 252 - 256
  • [45] Anti-idiotypic network involved in restoring ADAMTS13 activity in immune-mediated thrombotic thrombocytopenic purpura (iTTP)
    Heeb, Silvan Rolf
    Schaller, Monica
    Hovinga, Johanna Anna Kremer
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [46] In silico features of ADAMTS13 contributing to plasmatic ADAMTS13 levels in neonates with congenital heart disease
    Katneni, Upendra K.
    Holcomb, David D.
    Hernandez, Nancy E.
    Hamasaki-Katagiri, Nobuko
    Hunt, Ryan C.
    Bar, Haim
    Ibla, Juan C.
    Kimchi-Sarfaty, Chava
    THROMBOSIS RESEARCH, 2020, 193 : 66 - 76
  • [47] Correction of ADAMTS13 Deficiency by In Utero Gene Transfer of Lentiviral Vector encoding ADAMTS13 Genes
    Niiya, Masami
    Endo, Masayuki
    Shang, Dezhi
    Zoltick, Philip W.
    Muvarak, Nidal E.
    Cao, Wenjing
    Jin, Sheng-Yu
    Skipwith, Christopher G.
    Motto, David G.
    Flake, Alan W.
    Zheng, X. Long
    MOLECULAR THERAPY, 2009, 17 (01) : 34 - 41
  • [48] ADAMTS13 binds to CD36: a potential mechanism for platelet and endothelial localization of ADAMTS13
    Davis, Amanda K.
    Makar, Robert S.
    Stowell, Christopher P.
    Kuter, David J.
    Dzik, Walter H.
    TRANSFUSION, 2009, 49 (02) : 206 - 213
  • [49] Hypochlorous acid inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 activity during inflammation
    Fu, X.
    Wang, Y.
    Chen, J.
    Ling, M.
    Kulman, J. D.
    Lopez, J. A.
    Chung, D. W.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 964 - 964
  • [50] Genetic variants in the ADAMTS13 and SUPT3H genes are associated with ADAMTS13 activity
    de Vries, Paul S.
    Boender, Johan
    Sonneveld, Michelle A. H.
    Rivadeneira, Fernando
    Ikram, M. Arfan
    Rottensteiner, Hanspeter
    Hofman, Albert
    Uitterlinden, Andre G.
    Leebeek, Frank W. G.
    Franco, Oscar H.
    Dehghan, Abbas
    de Maat, Moniek P. M.
    BLOOD, 2015, 125 (25) : 3949 - 3955
12345