High-flow nasal cannula oxygen therapy in the weaning of severe burn patients: a preliminary report of data collection

Inpatient care of severely burned patients is associated with a high morbidity and mortality rate. Burns, especially severe ones, are accompanied by an immune and inflammatory response and drastic metabolic changes that are hard to manage, which can shortly lead to multiple organ failure as well as lung failure. Weaning from mechanical ventilation represents the transition period from total ventilatory support to spontaneous breathing and can be performed with different strategies. The objective of this prospective study is to evaluate the clinical conditions of a series of patients weaned from mechanical ventilation with the aid of high flow nasal cannulas.