Effects of Oral Cannabidiol on Health and Fitness in Healthy Adults: An 8-Week Randomized Trial

被引:8
|
作者
Flores, Victoria A. [1 ,2 ]
Kisiolek, Jacob N. [1 ,3 ]
Ramani, Arjun [1 ]
Townsend, Ryland [1 ]
Rodriguez, Edwin [1 ]
Butler, Blake [1 ]
Stewart, Laura K. [1 ]
机构
[1] Univ Northern Colorado, Dept Kinesiol Nutr & Dietet, Greeley, CO 80639 USA
[2] Univ Illinois, Dept Kinesiol & Nutr, Chicago, IL 60612 USA
[3] Univ Utah, Dept Pathol, Div Microbiol & Immunol, Salt Lake City, UT 84112 USA
关键词
cannabinoids; healthy adults; physical performance; cognition; psychological wellbeing; COGNITIVE FUNCTION; CANNABINOIDS;
D O I
10.3390/nu15122664
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: There is a lack of research on the effects of cannabidiol (CBD) on health-related fitness, physical activity, cognitive health, psychological wellbeing, and concentrations of C-reactive protein (CRP) in healthy individuals. CBD has potential anti-inflammatory and neuroprotective effects. Methods: This study aimed to investigate the effects of 8 weeks of CBD on the above-mentioned measures in healthy individuals. Forty-eight participants were randomized into two groups receiving either oral capsules of 50 mg of CBD or a calorie-matched placebo daily. Participants completed pre- and post-intervention assessments, including blood draws, body composition, fitness, physical activity, and self-reported surveys. Results: There were no significant differences between groups regarding body composition, aerobic fitness, muscular strength, physical activity, cognitive health, psychological wellbeing, and resting CRP concentrations. However, the placebo group experienced a decline in mean peak power and relative peak power compared to the CBD group. Conclusions: The results suggest that 8 weeks of CBD supplementation may prevent declines in anaerobic fitness over time. However, long-term CBD supplementation may not be beneficial for altering measures of health-related fitness, mental health, and inflammation in healthy individuals.
引用
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页数:13
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