New trend on antimicrobial activity of green AgNPs from Trogoderma granarium larval extract against antibiotic-resistant Salmonella Typhi

The development of green nanotechnology become very interest among researchers in order to synthesis eco-friendly of bionanoparticles. The current work used Trogoderma granarium larval extract as both a capping and reducing agent, as well as water as a solvent to biosynthesise stable silver nanoparticles (AgNPs). These biosynthesized nanoparticles were characterized with the help of atomic absorption spectroscopy (AAS UV-vis spectrophotometer), Zeta potential, Fourier infrared spectroscopy (FTIR), and atomic forced microscopy (AFM). It has been noted that within 5 minutes of reaction time, T. granarium larval extract can convert silver ions to silver nanoparticles. The antimicrobial activity of the AgNPs was screened against clinical isolate of multidrug-resistant Salmonella Typhi and showed inhibiting activities against Salmonella Typhi. As a result, this process may be utilized to produce rapid and eco-friendly stable silver nanoparticles with a size range of 59 nm which have antibacterial activity, suggesting that they could be exploited in the medical field.