OBJECTIVE: The purpose of this study is to use bibliometrics to explore the re-search overview and research hotspots.MATERIALS AND METHODS: The relevant literature on intestinal flora and diabetic ne-phropathy in the Web of Science Core Collec-tion was sorted out, and VOSviewer, CiteSpace, Scimago Graphica and other software were used to conduct data visualization analysis on the number of publications, countries, institutions, journals, authors, keywords and citations.RESULTS: A total of 124 relevant literatures were included. From 2015 to 2022, the number of published papers increased every year. The coun-tries, institutions and journals that published the most articles in this field are China, Isfahan University Medical Science and Frontiers in Pharma-cology. Liu Bicheng and Mirlohi Maryam are the authors with the most published articles in this field. The main keywords of research in this field are obesity, inflammation, oxidative stress, indox-yl sulfate, short-chain fatty acids (SCFAs) and Chi-nese herbal medicine.CONCLUSIONS: This is the first bibliometric analysis of diabetic nephropathy and gut micro -biota, reporting hot spots and emerging trends. Obesity, inflammation, oxidative stress, indox-yl sulfate, SCFAs and Chinese herbal medicine are the main keywords of current research, and SCFAs and Chinese herbal medicine may be the hotspots of future research.