Synapses shape oligodendrocyte precursor cell development and predict myelination location

被引：0
|
作者：
Li, Jiaxing [1 ]
Monk, Kelly R. [1 ]
机构：
[1] Vollum Inst, Portland, OR 97239 USA
来源：
NATURE NEUROSCIENCE | 2024年 / 27卷 / 02期
关键词：
D O I：
10.1038/s41593-023-01555-6
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Using in vivo imaging in zebrafish, we unveiled critical components (PSD-95, gephyrin and neuroligin-3) and dynamic properties of synapses between neurons and oligodendrocyte precursor cells (OPC). Furthermore, we showed that neuron-OPC synapses have a pivotal role in regulating OPC development and CNS myelination.
引用
收藏
页码：217 / 218
页数：2
相关论文
共 50 条
  • [21] A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain
    Dazhi Guo
    Fei Huang
    Ruijun Xue
    Yuehong Ma
    Lin Xiao
    Huifang Lou
    Shuyi Pan
    Molecular Neurobiology, 2023, 60 : 1675 - 1689
  • [22] Regulation of synaptic connectivity of oligodendrocyte precursor cells in myelination and myelin repair
    Angulo, M. C.
    GLIA, 2015, 63 : E57 - E58
  • [23] Nanofibers Support Oligodendrocyte Precursor Cell Growth and Function as a Neuron-Free Model for Myelination Study
    Li, Yongchao
    Ceylan, Muhammet
    Shrestha, Bikesh
    Wang, Haibo
    Lu, Q. Richard
    Asmatulu, Ramazan
    Yao, Li
    BIOMACROMOLECULES, 2014, 15 (01) : 319 - 326
  • [24] Oligodendrocyte Precursor Cell Transplantation into Organotypic Cerebellar Shiverer Slices: A Model to Study Myelination and Myelin Maintenance
    Bin, Jenea M.
    Leong, Soo Yuen
    Bull, Sarah-Jane
    Antel, Jack P.
    Kennedy, Timothy E.
    PLOS ONE, 2012, 7 (07):
  • [25] THE EXPRESSION PROFILE OF OLIGODENDROCYTE PRECURSOR CELL MARKERS IN DEVELOPMENT AND DISEASE
    Sitnikov, S.
    Spitzer, S.
    Na, J.
    Luzhynskaya, A.
    Karadottir, R.
    GLIA, 2011, 59 : S48 - S49
  • [26] THE OLIGODENDROCYTE SPECIFIC TRANSCRIPTIONAL REGULATOR MRF IS VITAL FOR OLIGODENDROCYTE DEVELOPMENT AND CNS MYELINATION
    Emery, B.
    Agalliu, D.
    Cahoy, J.
    Mulinyawe, S.
    Barres, B. A.
    JOURNAL OF NEUROCHEMISTRY, 2009, 108 : 29 - 29
  • [27] Role of SIRT2 in oligodendrocyte development and myelination
    Thangaraj, M. P.
    Doucette, J. R.
    Ji, S.
    Nazarali, A. J.
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2015, 47 : 87 - 88
  • [28] Oligodendrocyte development myelination in GFP-transgenic and zebrafish
    Yoshida, M
    Macklin, WB
    JOURNAL OF NEUROSCIENCE RESEARCH, 2005, 81 (01) : 1 - 8
  • [29] Myelination of regenerating optic nerve axons occurs in conjunction with an increase of the oligodendrocyte precursor cell population in the adult mice
    Mendonca, Henrique Rocha
    Goulart Villas Boas, Camila Oliveira
    Heringer, Luiza dos Santos
    Oliveira, Julia Teixeira
    Blanco Martinez, Ana Maria
    BRAIN RESEARCH BULLETIN, 2021, 166 : 150 - 160
  • [30] Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination
    Pan, Lin
    Trimarco, Amelia
    Zhang, Alice J.
    Fujimori, Ko
    Urade, Yoshihiro
    Sun, Lu O.
    Taveggia, Carla
    Zhang, Ye
    Monk, Kelly
    ELIFE, 2023, 12
12345