Analysis of Fluorescence Collection Efficiency for Fiber-optic Scanning Two-photon Endomicroscopy

被引：0
|
作者：
Wang, Conghao [1 ]
Liu, Huilan [1 ,2 ]
Wang, Aimin [3 ]
Feng, Lishuang [1 ,2 ,4 ]
机构：
[1] Beihang Univ, Sch Instrumentat & Optoelect Engn, Beijing 100191, Peoples R China
[2] Minist Educ, Key Lab Precis Opto Mechatron Technol, Beijing 100191, Peoples R China
[3] Peking Univ, Sch Elect, State Key Lab Adv Opt Commun Syst & Networks, Beijing 100871, Peoples R China
[4] Beihang Univ, Hangzhou Innovat Inst, Lab Intelligent Sensing Mat & Chip Integrat Techn, Hangzhou 310063, Peoples R China
来源：
SPIE-CLP CONFERENCE ON ADVANCED PHOTONICS 2022 | 2023年 / 12601卷
关键词：
two-photon endomicroscopy; collection efficiency; double-cladding fiber; piezoelectric ceramic scanning; MICROSCOPY;
D O I：
10.1117/12.2667161
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Piezoelectric ceramic tube fiber-scanning two-photon endomicroscopy is an essential division of miniature two-photon microscopy. The reverse collection optical path of the two-photon endomicroscopy platform is modeled and designed in this study. After simulating the chromatic aberration characteristics of the objective, the effects of the collection signal wavelengths, off-axis positions, fiber cladding diameters, and imaging depths on the collection efficiency are evaluated using Monte Carlo simulation. The results provide an additional theoretical explanation for enhancing the two-photon endomicroscopy platform's imaging sensitivity and signal-to-noise ratio.
引用
收藏
页数：5
相关论文
共 50 条
  • [41] Fiber-optic fluorescence imaging
    Flusberg, BA
    Cocker, ED
    Piyawattanametha, W
    Jung, JC
    Cheung, ELM
    Schnitzer, MJ
    NATURE METHODS, 2005, 2 (12) : 941 - 950
  • [42] Fiber-optic fluorescence imaging
    Benjamin A Flusberg
    Eric D Cocker
    Wibool Piyawattanametha
    Juergen C Jung
    Eunice L M Cheung
    Mark J Schnitzer
    Nature Methods, 2005, 2 : 941 - 950
  • [43] High-speed fiber-optic scanning nonlinear endomicroscopy for imaging neuron dynamics in vivo
    Park, Hyeon-Cheol
    Guan, Honghua
    Li, Ang
    Yue, Yuanlei
    Li, Ming-Jun
    Lu, Hui
    Li, Xingde
    OPTICS LETTERS, 2020, 45 (13) : 3605 - 3608
  • [44] Fiber-optic laser scanning confocal microscope suitable for fluorescence imaging
    Delaney, Peter M.
    Harris, Martin R.
    King, Roger G.
    Applied Optics, 1994, 33 (04): : 573 - 377
  • [45] Two-Color Two-Photon Fluorescence Laser Scanning Microscopy
    S. Quentmeier
    S. Denicke
    K.-H. Gericke
    Journal of Fluorescence, 2009, 19 : 1037 - 1043
  • [46] Two-Color Two-Photon Fluorescence Laser Scanning Microscopy
    Quentmeier, S.
    Denicke, S.
    Gericke, K. -H.
    JOURNAL OF FLUORESCENCE, 2009, 19 (06) : 1037 - 1043
  • [47] Construction of fiber-optic bundle light-collection systems and calculations of collection efficiency
    DiBerardino, D
    Rafac, RJ
    Bone, S
    Gerginov, VP
    Tanner, CE
    OPTICS COMMUNICATIONS, 2002, 210 (3-6) : 233 - 243
  • [48] Establishment and analysis of scanning model of a wavelength scanning fiber-optic interferometer
    Wang, Yong
    Liao, Yanbiao
    Tian, Qian
    Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves, 1998, 17 (06): : 459 - 464
  • [49] Lensed fiber-optic probe design for efficient photon collection in scattering media
    Ryu, Youngjae
    Shin, Younghoon
    Lee, Dasol
    Altarejos, Judith Y.
    Chung, Euiheon
    Kwon, Hyuk-Sang
    BIOMEDICAL OPTICS EXPRESS, 2015, 6 (01): : 191 - 210
  • [50] Establishment and analysis of scanning model of a wavelength scanning fiber-optic interferometer
    Wnag, Y
    Liao, YB
    Tian, Q
    JOURNAL OF INFRARED AND MILLIMETER WAVES, 1998, 17 (06) : 459 - 464
12345