Severe Jarisch-Herxheimer Reaction (JHR) in a leptospirosis patient: A case report

被引：0

作者：

Zhao, Ruo-Yan ^{[1
,3
]}

Liu, Meng -Die ^{[2
,3
]}

Lin, Ying-Xin ^{[3
]}

Huang, Lei ^{[3
,4
]}

机构：

[1] Hubei Univ Med, Shiyan 442000, Hubei, Peoples R China

[2] Shenzhen Univ, Shenzhen 518000, Guangdong, Peoples R China

[3] Peking Univ, Shenzhen Hosp, Intens Care Unit, Shenzhen 518000, Guangdong, Peoples R China

[4] Peking Univ, Shenzhen Hosp, Intens Care Unit, 1120 Lianhua Rd, Shenzhen 518000, Guangdong, Peoples R China

来源：

HELIYON | 2024年 / 10卷 / 03期

关键词：

Leptospirosis; Jarisch-Herxheimer reaction; Acute respiratory distress syndrome; Acute renal failure; Case report;

D O I：

10.1016/j.heliyon.2024.e24538

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Leptospirosis is a zoonosis that is related to potential respiratory, renal, neurological, and cardiovascular failure. At present, antibiotics are the recommended treatment, but due to the underlying cause of the disease, they may induce the Jarisch-Herxheimer reaction (JHR) within 24 hours. At the same time, we speculate that JHR may aggravate the natural course of leptospirosis. Considering that there are few available reports on this event, we will share a case of pulmonary hemorrhagic leptospirosis, where antibiotic treatment is suspected to have triggered the JHR. This report is expected to improve clinical attention to the relationship between leptospirosis and JHR.

引用

页数：5

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