B(C6F5)3-mediated direct intramolecular C7-alkenylation of N-propargylindoles

被引：2

作者：

Cui, Jie ^{[1
]}

Wang, Tongdao ^{[1
]}

机构：

[1] Dalian Univ Technol, Sch Chem, Dalian 116024, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 68期

基金：

中国国家自然科学基金;

关键词：

C-H; INDOLE ALKALOIDS; C7-FUNCTIONALIZATION; FUNCTIONALIZATION; REARRANGEMENT; ALKYLATION; ACTIVATION; REACTIVITY; ARYLATION; AMINES;

D O I：

10.1039/d3cc02599c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

B(C6F5)(3)-mediated direct C7-alkenylation of N-propargylindoles without directing groups was developed. This reaction proceeds via the & pi;-activation of the alkynyl group with B(C6F5)(3)/Friedel-Crafts alkenylation/proton transfer reaction sequence. Interestingly, C7-alkenylation products could further convert into the fused indoles by deprotonation and finally polyaromatic N-heterocycles by the hydride abstraction.

引用

页码：10279 / 10282

页数：4

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