A rhesus macaque model of human norovirus infection

被引：0
|
作者：
Rimkute, Inga [1 ]
Roederer, Mario [1 ]
机构：
[1] Natl Inst Allergy & Infect Dis NIAID, Natl Inst Hlth NIH, Vaccine Res Ctr, Bethesda, MD 20892 USA
来源：
NATURE MICROBIOLOGY | 2024年 / 9卷 / 03期
关键词：
D O I：
10.1038/s41564-023-01597-3
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Human norovirus infection is a major global health concern, but a suitable animal model is lacking. We have established repeated infection with human norovirus in rhesus macaques via oral challenge. Animals demonstrate virus shedding in the stool and subsequent serum antibody responses, and virus replication is detected in the small intestine.
引用
收藏
页码：593 / 594
页数：2
相关论文
共 50 条
  • [21] The Rhesus Macaque as an Animal Model for Human Nutrition: An Ecological-Evolutionary Perspective
    Cui, Zhenwei
    Dong, Yunlong
    Sholl, Jonathan
    Lu, Jiqi
    Raubenheimer, David
    ANNUAL REVIEW OF ANIMAL BIOSCIENCES, 2025, 13 : 441 - 464
  • [22] The aged female rhesus macaque as a translational model for human menopause and hormone therapy
    Kohama, Steven G.
    Urbanski, Henryk F.
    HORMONES AND BEHAVIOR, 2024, 166
  • [23] HSPC EDITING IN THE RHESUS MACAQUE TO MODEL HUMAN BIOLOGY AND TO DEVELOP NEW THERAPIES
    Dunbar, Cynthia
    EXPERIMENTAL HEMATOLOGY, 2020, 88 : S19 - S19
  • [24] Non-human primate model of transient global ischemia in Rhesus Macaque
    Hara, Koichi
    Yasuhara, Takao
    Matsukawa, Noriyuki
    Rodriguez, Nancy A.
    Yamashima, Tetsumori
    Buccafusco, Jerry J.
    Kawase, Takeshi
    Hess, David C.
    Borlongan, Cesario V.
    NEUROSCIENCE RESEARCH, 2008, 61 : S281 - S281
  • [25] THE PECULIAR EVOLUTION OF APOLIPOPROTEIN(A) IN HUMAN AND RHESUS MACAQUE
    PESOLE, G
    GERARDI, A
    DIJESO, F
    SACCONE, C
    GENETICS, 1994, 136 (01) : 255 - 260
  • [26] Chimpanzees as an animal model for human norovirus infection and vaccine development
    Bok, Karin
    Parra, Gabriel I.
    Mitra, Tanaji
    Abente, Eugenio
    Shaver, Charlene K.
    Boon, Denali
    Engle, Ronald
    Yu, Claro
    Kapikian, Albert Z.
    Sosnovtsev, Stanislav V.
    Purcell, Robert H.
    Green, Kim Y.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (01) : 325 - 330
  • [27] Experimental miniature piglet model for the infection of human norovirus GII
    Seo, Dong Joo
    Jung, Day
    Jung, Soontag
    Ha, Seung-Kwon
    Ha, Sang-Do
    Choi, In-Soo
    Myoung, Jinjong
    Choi, Changsun
    JOURNAL OF MEDICAL VIROLOGY, 2018, 90 (04) : 655 - 662
  • [28] Rhesus macaque model for ovarian cancer chemoprevention
    Brewer, M
    Baze, W
    Hill, L
    Utzinger, U
    Wharton, JT
    Follen, M
    Khan-Dawood, F
    Satterfield, W
    COMPARATIVE MEDICINE, 2001, 51 (05) : 424 - 429
  • [29] The rhesus macaque as a preclinical model for HIV comorbidities
    Roberts, C. T.
    Sacha, J.
    Kievit, P.
    ANTIVIRAL THERAPY, 2018, 23 : A67 - A67
  • [30] A rhesus macaque model of Streptococcus pneumoniae carriage
    Philipp, M. T.
    Doyle, L. A.
    Martin, D. S.
    Plauche, G. B.
    Phillippi-Falkenstein, K. M.
    Bohm, R. P., Jr.
    JOURNAL OF MEDICAL PRIMATOLOGY, 2012, 41 (01) : 60 - 66
12345