Ketone bodies as treatments for neurological illnesses

被引:0
|
作者
Arango-Morales, David [1 ,2 ]
Arango-Morales, Nidia [1 ,3 ]
机构
[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Cirugia Expt, Mexico City, Mexico
[2] Inst Politecn Nacl, Escuela Super Med, Mexico City, Mexico
[3] Univ Nacl Autonoma Mexico, Fac Med, Mexico City, Mexico
来源
REVISTA MEXICANA DE NEUROCIENCIA | 2023年 / 24卷 / 02期
关键词
Ketone bodies; 6-hydroxybutyrate; Ketogenic diet; Inflammasome; Neuroprotection; KETOGENIC DIET; METABOLISM; BRAIN;
D O I
10.24875/RMN.22000062
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Ketone bodies such as 6-hydroxybutyrate, acetoacetate, and acetone are produced mainly in the liver from fatty acids. In this way, they can be used by the body as an alternate source of energy. However, their properties go beyond an alternate source of energy. For many years, ketogenic therapies have been implemented for the treatment of certain neurological diseases, such as epilepsy. History shows us that its implementations were beneficial, minimizing the severity of seizures despite ignoring their mechanisms of action. At present, their applications and mechanisms are beginning to be understood.
引用
收藏
页码:52 / 57
页数:6
相关论文
共 50 条
  • [31] Ketone bodies as signaling metabolites
    Newman, John C.
    Verdin, Eric
    TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2014, 25 (01): : 42 - 52
  • [32] Ketone bodies for the starving heart
    Schulze, P. Christian
    Wu, Jasmine M. F.
    NATURE METABOLISM, 2020, 2 (11) : 1183 - 1185
  • [33] CHEMICAL ESTIMATION OF KETONE BODIES
    BRITTON, HG
    ANALYTICAL BIOCHEMISTRY, 1966, 15 (02) : 261 - &
  • [34] Ketone bodies as epigenetic modifiers
    Ruan, Hai-Bin
    Crawford, Peter A.
    CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2018, 21 (04): : 260 - 266
  • [35] Metabolic Messengers: ketone bodies
    Alisa B. Nelson
    Eric D. Queathem
    Patrycja Puchalska
    Peter A. Crawford
    Nature Metabolism, 2023, 5 : 2062 - 2074
  • [36] The distribution of ketone bodies in tissues
    Harrison, HC
    Long, CNH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1940, 133 (01) : 209 - 218
  • [37] Treatments for skeletal muscle abnormalities in heart failure: sodium-glucose transporter 2 and ketone bodies
    Takada, Shingo
    Sabe, Hisataka
    Kinugawa, Shintaro
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2022, 322 (02): : H117 - H128
  • [38] THE USE OF SOMATIC TREATMENTS FOR PSYCHIATRIC ILLNESSES
    KLERMAN, GL
    PSYCHOPHARMACOLOGY BULLETIN, 1986, 22 (02) : 455 - 456
  • [39] MENTAL AND NEUROLOGICAL DIVIDE Suggested merger of mental and neurological illnesses is premature
    Bailey, Sue
    Burn, Wendy
    Craddock, Nick
    Mynors-Wallis, Laurence
    Tyrer, Peter
    BRITISH MEDICAL JOURNAL, 2012, 345