Molecularly imprinted polymer/graphene oxide modified glassy carbon electrode for selective detection of sulfanilamide

A novel sensitive electrochemical sensor based on a glassy carbon electrode（GCE） modified with molecularly imprinted polymer（MIP） and grapheme oxide（GO） was developed.The MIP/GO material was prepared by precipitation polymerization in the presence of sulfanilamide as template molecule.The MIP/GO based electrochemical sensor was characterized using scanning electron microscopy（SEM）,cyclic voltammetry（CV）,electrochemical impedance spectroscopy（EIS） and square wave voltammetry（SWV）.The results indicated that the sensor exhibited good affinity and excellent electrochemical response for sulfanilamide.Under optimized conditions,the oxidation peak current intensity of sulfanilamide showed two linear dynamic ranges from 10 to 1000 ng mL;,and the standard deviation was less than 5% using SWV method.The sensor displays good stability,reproducibility,and high sensitivity.It can be further applied to quantify sulfanilamide in milk.