INTERVENTION CHEMOTHERAPY IN COMPREHENSIVE TREATMENT OF ADVANCED NASOPHARYNGEAL CARCINOMA

被引：0
|
作者：
崔英
马亦龙
王安宇
许坚
赖少侣
齐锋
李伟
张则
机构：
来源：
Chinese Journal of Cancer Research | 2000年 / 02期
关键词：
Nasopharyngeal carcinoma; Interventional chemotherapy; Comprehensive treatment;
D O I：
暂无
中图分类号：
R739.63 [咽肿瘤];
学科分类号：
100214 ;
摘要：
Objective: To study the use of interventional chemotherapy in comprehensive treatment for advanced nasopharyngeal carcinoma. Methods: Interventional chemotherapy with multi-drugs including cisplatin (DDP) 100 mg, 5-fluorouracil (5-FU) 1000 mg and bleomycin (BLM) 16 mg was used to treat 30 cases with advanced nasopharyngeal carcinoma before radiotherapy. 50 cases that received radiotherapy alone were used as a control group. The methods, time and dose schedule of radiotherapy were similar in the two groups. Results: The primary lesions in 16 cases and the cervical lymph nodes in 12 cases were reduced in size after interventional chemotherapy. Radiation doses of those in complete response in their primary lesion and cervical lymph nodes were lower than that of the control group (P<0.05). The complete response rate of study group was 83.3% and that of control group was 72.0% (P<0.05). Conclusion: Interventional chemotherapy plus radiotherapy is a valuable treatment method in advanced nasopharyngeal carcinoma.
引用
收藏
页码：141 / 143
页数：3
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