Comparable investigation in dopamine transporters with 99mTc-TRODAT-1 and 131I-FP-CIT SPECT in Parkinson’s disease patients

被引：0
|
作者：
LIU Congjin1 LIU Xingdang1* ZHANG Guangming1 LI Ding1 WANG Jian2 YANG Liqin2 JIANG Yuping2 (1 Department of Nuclear Medicine
2 Department of Neurology
机构：
来源：
NuclearScienceandTechniques | 2007年 / 04期
关键词：
99mTc-TRODAT-1; SPECT; 131I-FP-CIT SPECT; Parkinson’s disease;
D O I：
暂无
中图分类号：
R742.5 [震颤麻痹综合征]; R817.4 [在诊断上的应用];
学科分类号：
1001 ; 100105 ; 1002 ; 100207 ; 100602 ;
摘要：
Dopamine transporter (DAT) mediates the regulation of dopaminergic function. Two agents of TRODAT-1 and FP-CIT were observed in evaluating DAT change of Parkinson’s disease (PD). The relationship between them was also evaluated. The results suggested that 99mTc-TRODAT-1 SPECT and 131I-FP-CIT SPECT may serve as sensitive and objective in vivo markers to reflect the severity of PD. The 99mTc-TRODAT-1 image is more accurate and clearer compared with 131I-FP-CIT.
引用
收藏
页码：232 / 236
页数：5
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