PROTECTIVE EFFECTS OF PENTAGASTRIN AGAINST STRESS-INDUCED GASTRIC LESIONS IN RATS

被引：0
|
作者：
李栋生
戴义隆
陈启盛
肖强
朱启绽
机构：
来源：
中华医学杂志(英文版) | 1986年 / 06期
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中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The rats, pretreated with pentagastrin, 250 μg/kg,daily for 7 days, were given restraint water immersion stress for 3 hours and observed for lesion index of the gastric mucosa. The results showed that the lesion index of the pentagastrin group was significantly decreased as compared with that of the control group. Light and electron microscopically,the mucosal layer was thickened and both the chief cells and parietal cells were in an active state. This suggests that gastrin has protective effects against the stress-induced gastric lesions through its trophic action on the gastrointestinal tract.
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页码：457 / 460
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