Role of miRNA in Mammary Gland Development and Lactation

被引：1
|
作者：
Li Qing-zhang [1 ]
Wang Chun-mei [1 ]
Gao Xue-jun [1 ]
机构：
[1] Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University
来源：
Journal of Northeast Agricultural University(English Edition) | 2014年 / 21卷 / 01期
关键词：
miRNA; epigenetic; mammary gland; milk production;
D O I：
暂无
中图分类号：
S823 [牛];
学科分类号：
摘要：
miRNA can regulate development and milk yield of the mammary gland through epigenetic mechanism.miRNA can directly and indirectly modulate the activity of the epigenetic machinery,target genes through post-inhibition of translation initiation,mediate miRNA decay,target genes and inhibit the positive regulation,regulate tone modification,and regulate DNA methylation of target genes.Here we reviewed the role of miRNAs in mammary gland development and lactation.Researching miRNA in mammary gland development and lactation process,and understanding the response of the epigenetic mechanisms to external stimuli will be an important necessity to devise new technologies for maximizing their activity and milk production in the dairy cow.
引用
收藏
页码：70 / 74
页数：5
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