Interaction between fulvic acids of different origins and active oxygen radicals

被引:0
|
作者
王春霞
王子健
彭安
侯京武
忻文娟
机构
[1] Beijing 100085
[2] Research Center for Eco-Environmental Sciences
[3] Institute of Biophysics
[4] China
[5] China)
[6] State Key Laboratory of Environmental Aquatic Chemistry
[7] Beijing 100101
[8] Chinese Academy of Sciences
基金
中国国家自然科学基金;
关键词
fulvic acids; active oxygen radicals; spin trapping; Kaschin-Beck disease;
D O I
暂无
中图分类号
Q592 [体液化学];
学科分类号
071010 ; 081704 ;
摘要
Using the spin trapping technique, the interaction between fulvic acids (FAs) of different origins and the active oxygen radicals was studied. The active oxygen radicals under study included superoxide anion (O2 · -) produced by xanthine oxidase (XOD) and stimulated polymorphonuclear leukocytes (PMN) of human being and hydroxyl radical ( ·OH) produced from Fenton’s reaction. It has been found that the FAs from both Kaschin-Beck disease (KBD) region and non-KBD region can accelerate the production of ·OH and scavenge O2 ·- . FA from peat can scavenge both O2·- and ·OH. The results show that the behavior of KBD and non-KBD FAs differs clearly from peat FA. It has been concluded that the superoxidation damage of KBD induced by FA is mainly due to hydroxyl radical reaction initiated in biological system.
引用
收藏
页码:267 / 275
页数:9
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