ANTIGEN MG7 IN GASTRIC CANCER AND GASTRIC PRECANCEROUS LESIONS

被引：0
|
作者：
郭冬丽
宁佩芳
袁媛
机构：
[1] The First Affiliated Hospital
[2] China Medical University Shenyang 110001
[3] China Medical University
[4] Cancer Institute
来源：
Chinese Journal of Cancer Research | 2004年 / 01期
关键词：
MG7; antigen; Gastric cancer; Gastric precancerous lesions; Diagnosis;
D O I：
暂无
中图分类号：
R735.2 [胃肿瘤];
学科分类号：
摘要：
Objective: To study the dynamic change and its diagnostic significance of MG7 expression in the process of gastric cancer development. Methods: The expression level of antigen MG7 was determined by immunohistochemistry method in 406 cases of gastric mucosa. The classification of intestinal metaplasia of gastric mucosa was determined by histochemistry method in 82 cases. Results: The positive rate of MG7 expression in normal gastric mucosa, intestinal metaplasia and dysplasia of gastric mucosa and gastric cancer were increased gradually (P<0.01). The positive rate of MG7 expression in superficial gastritis, atrophic gastritis and gastric cancer were increased on sequence (P<0.01). The positive rate of antigen MG7 expression in type III intestinal metaplasia of gastric mucosa had significant difference, compared with that in type I an II intestinal metaplasia (P<0.05). Conclusion: MG7 antigen had close relationship with gastric cancer. Type III intestinal metaplasia, atrophic gastritis and dysplasia should be followed up in order to improve the early detection of gastric cancer. MG7 antigen had great clinical value in the dynamic follow-up of gastric precursors.
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页码：4 / 7
页数：4
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