PPA-SiO2 catalyzed efficient synthesis of polyhydroquinoline derivatives through Hantzsch multicomponent condensation under solvent-free conditions

被引：0

作者：

Amir Khojastehnezhad ^{[1
]}

Farid Moeinpour ^{[2
]}

Abolghasem Davoodnia ^{[1
]}

机构：

[1] Department of Chemistry,Faculty of Sciences,Islamic Azad University,Mashhad Branch,Mashhad 91735-413,Iran

[2] Department of Chemistry,Faculty of Sciences,Islamic Azad University,Bandar Abbas Branch,Iran

来源：

Chinese Chemical Letters | 2011年 / 22卷 / 07期

关键词：

Multicomponent reaction; One-pot synthesis; Solvent-free; Polyhydroquinoline derivatives; Silica-supported polyphosphoric acid（PPA-SiO2）;

D O I：

暂无

中图分类号：

O621.3 [有机合成化学];

学科分类号：

摘要：

Silica gel-supported polyphosphoric acid(PPA-SiO) was found to be an efficient catalyst for the one-pot four-component Hantzsch condensation reaction of aryl aldehydes,dimedone,ethyl acetoacetate and ammonium acetate to afford the corresponding polyhydroquinoline derivatives in high yields.The main advantages of the present approach are short reaction times,clean reaction profiles,simple experimental and workup procedures.

引用

页码：807 / 810

页数：4

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