Endonuclease modified comet assay for oxidative DNA damage induced by detection of genetic toxiants

被引：0
|
作者：
赵健 [1 ]
机构：
[1] Key Lab Chem Safe & Health,Chin Dis Contr & Prev Center
来源：
ChinaMedicalAbstracts(InternalMedicine) | 2014年 / 31卷 / 02期
关键词：
Endonuclease modified comet assay for oxidative DNA damage induced by detection of genetic toxiants; DNA;
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Objective The aim of this study was to investigate the use of the lesion-specific endonucleases-modifiedcomet assay for analysis of DNA,oxidation in cell lines.Methods DNA breaks and oxidative damage were evaluated by normal alkaline and formamidopyrimidine-DNAglycosylase(FPG)modified comet assays.Cytotoxicity was assessed by MTT method.The human bronchial epi-
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页码：66 / 66
页数：1
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