Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity

被引：0

作者：

Juanjuan Feng ^{[1
]}

Mingjin Rao ^{[1
]}

Man Wang ^{[2
]}

Lin Liang ^{[2
]}

Zhi Chen ^{[1
]}

Xiufeng Pang ^{[1
]}

Weiqiang Lu ^{[1
]}

Zhenliang Sun ^{[2
]}

机构：

[1] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University

[2] Shanghai University of Medicine & Health Sciences Affiliated Sixth People's Hospital South Campus

来源：

Science China(Life Sciences) | 2019年 / 10期

基金：

中国国家自然科学基金;

关键词：

GLI; Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity;

D O I：

暂无

中图分类号：

R285 [中药药理学]; Q25 [细胞生理学];

学科分类号：

摘要：

Dear Editor,Pancreatic cancer (PCa) is a high-grade gastrointestinal malignancy more commonly occurring in elderly populations with lower than 5% overall 5-year survival rate (Hidalgo, 2010). PCa responds poorly to most chemotherapeutic agents, and therefore it is imperative to develop novel therapeutic agents that have anti-cancer activities against PCa.

引用

页码：1409 / 1412

页数：4

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