Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity

被引：0

作者：

Juanjuan Feng ^{[1
]}

Mingjin Rao ^{[1
]}

Man Wang ^{[2
]}

Lin Liang ^{[2
]}

Zhi Chen ^{[1
]}

Xiufeng Pang ^{[1
]}

Weiqiang Lu ^{[1
]}

Zhenliang Sun ^{[2
]}

机构：

[1] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University

[2] Shanghai University of Medicine & Health Sciences Affiliated Sixth People's Hospital South Campus

来源：

Science China(Life Sciences) | 2019年 / 10期

基金：

中国国家自然科学基金;

关键词：

GLI; Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity;

D O I：

暂无

中图分类号：

R285 [中药药理学]; Q25 [细胞生理学];

学科分类号：

摘要：

Dear Editor,Pancreatic cancer (PCa) is a high-grade gastrointestinal malignancy more commonly occurring in elderly populations with lower than 5% overall 5-year survival rate (Hidalgo, 2010). PCa responds poorly to most chemotherapeutic agents, and therefore it is imperative to develop novel therapeutic agents that have anti-cancer activities against PCa.

引用

页码：1409 / 1412

页数：4

共 50 条

[1] Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity
Juanjuan Feng
Mingjin Rao
Man Wang
Lin Liang
Zhi Chen
Xiufeng Pang
Weiqiang Lu
Zhenliang Sun
Science China Life Sciences, 2019, 62 : 1409 - 1412
[2] Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity
Juanjuan Feng
Mingjin Rao
Man Wang
Lin Liang
Zhi Chen
Xiufeng Pang
Weiqiang Lu
Zhenliang Sun
Science China(Life Sciences), 2019, 62 (10) : 1409 - 1412
[3] Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity
Feng, Juanjuan
Rao, Mingjin
Wang, Man
Liang, Lin
Chen, Zhi
Pang, Xiufeng
Lu, Weiqiang
Sun, Zhenliang
SCIENCE CHINA-LIFE SCIENCES, 2019, 62 (10) : 1409 - 1412
[4] Hedgehog signaling pathway regulates human pancreatic cancer cell proliferation and metastasis
Hao, Kun
Tian, Xiao-Dong
Qin, Chang-Fu
Xie, Xue-Hai
Yang, Yin-Mo
ONCOLOGY REPORTS, 2013, 29 (03) : 1124 - 1132
[5] LINC00671 suppresses cell proliferation and metastasis in pancreatic cancer by inhibiting AKT and ERK signaling pathway
Shibin Qu
Kunwei Niu
Jianlin Wang
Jimin Dai
Anutosh Ganguly
Chao Gao
Yuzi Tian
Zhibin Lin
Xisheng Yang
Xuan Zhang
Zhengcai Liu
Haimin Li
Cancer Gene Therapy, 2021, 28 : 221 - 233
[6] LINC00671 suppresses cell proliferation and metastasis in pancreatic cancer by inhibiting AKT and ERK signaling pathway
Qu, Shibin
Niu, Kunwei
Wang, Jianlin
Dai, Jimin
Ganguly, Anutosh
Gao, Chao
Tian, Yuzi
Lin, Zhibin
Yang, Xisheng
Zhang, Xuan
Liu, Zhengcai
Li, Haimin
CANCER GENE THERAPY, 2021, 28 (3-4) : 221 - 233
[7] Narciclasine suppresses esophageal cancer cell proliferation and migration by inhibiting the FAK signaling pathway
Qiu, Yinda
Fang, Bo
Thuy, Nguyen Thi Thanh
Li, Aoding
Yoo, Hee Min
Zheng, Xiaohui
Cho, Namki
EUROPEAN JOURNAL OF PHARMACOLOGY, 2022, 921
[8] LHPP suppresses proliferation, migration, and invasion in hepatocellular carcinoma and pancreatic cancer by inhibiting EGFR signaling pathway
Zhu, Haitao
Song, Chunzhuo
Li, Junjun
Liu, Qianfan
Liu, Meng
Fu, Liyue
MEDICAL ONCOLOGY, 2023, 40 (09)
[9] 5-Azacytidine suppresses the proliferation of pancreatic cancer cells by inhibiting the Wnt/β-catenin signaling pathway
Zhang, H.
Zhou, W. C.
Li, X.
Meng, W. B.
Zhang, L.
Zhu, X. L.
Zhu, K. X.
Bai, Z. T.
Yan, J.
Liu, T.
Xu, X. C.
Li, Y. M.
GENETICS AND MOLECULAR RESEARCH, 2014, 13 (03) : 5064 - 5072
[10] LHPP suppresses proliferation, migration, and invasion in hepatocellular carcinoma and pancreatic cancer by inhibiting EGFR signaling pathway
Haitao Zhu
Chunzhuo Song
Junjun Li
Qianfan Liu
Meng Liu
Liyue Fu
Medical Oncology, 40

← 1 2 3 4 5 →