Neoadjuvant therapy strategies for advanced gastric cancer: Current innovations and future challenges

被引：5
|
作者：
Zhu Zhi
Gong Ying-Bo
Xu Hui-Mian
机构：
[1] Department of Surgical Oncology
[2] Shenyang
[3] ChinaDepartment of Surgical Oncology
[4] The First Hospital of China Medical University
[5] Liaoning 110001
来源：
慢性疾病与转化医学（英文） | 2020年 / 06卷 / 03期
关键词：
Gastric cancer; Neoadjuvant therapy; Chemotherapy; Radiotherapy;
D O I：
暂无
中图分类号：
R735.2 [胃肿瘤];
学科分类号：
100214 ;
摘要：
Gastric cancer, which has a high incidence and poor prognosis, remains a therapeutic challenge. Recently, neoadjuvant therapy has attracted increasing attention due to high recurrence rate and low survival rate after resection in most patients with advanced stage. Clinical trials show that neoadjuvant approaches confer a significant survival advantage for resectable locally advanced gastric cancer. The specific advantages of chemoradiotherapy compared with chemotherapy have not been clarified; optimal regimens and cycles, particularly in the preoperative setting, should be studied further; and trials aimed at determining the role of targeted and immunological therapies should be conducted.
引用
收藏
页码：147 / 157
页数：11
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