Objective To estimate the incidence and establish clinicopathological, immunohistochemical , diagnostic and therapeutic features in children with solid cystic papillary tumor (SCPT) of the pancreas in children. Methods Eleven cases (male 1,frmale 10) aging from 9 to 14 years with a mean of 11.1 years with SCPT were analyzed. The chief complains were abdominal pain and palpable mass. The tumors were often located in the head of pancreas. The mean diameter of tumors was 8. 7 cm. The procedures employed included local resections (6), distal pancreatectomy (2) and pancreatico-duodenectomies (3). Routine pathological, histochemical, and immunohistochemical methods were utilized to analyze the specimens. Representative blocks of SCPT specimens were immunostained for NSE, α-1 AT, S - 100, CgA, CK, EMA and insulin. Results The patients were followed-up for 1 to 15 years and were alive postoperatively. Histological examination showed solid with cystic areas and papillary protrusions. Immunohistochemically, the p