Analysis of Gene Expression Profile in Lung Adenosquamous Carcinoma Using cDNA Microarray

被引：0
|
作者：
YANG Fei 1
2. Department of Respiratory Medicine
机构：
来源：
WuhanUniversityJournalofNaturalSciences | 2004年 / 06期
关键词：
lung carcinoma; adenosquamous carcinoma; microarray; gene expression profile;
D O I：
暂无
中图分类号：
R734.2 [肺肿瘤];
学科分类号：
100214 ;
摘要：
Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosquamous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-oncogenes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.
引用
收藏
页码：967 / 972
页数：6
相关论文
共 50 条
  • [31] Analysis of Gene Expression Profile of Limonium bicolor under NaHCO3 Stress Using cDNA Microarray
    Wang, Yucheng
    Ma, Hui
    Liu, Guifeng
    Xu, Chenxi
    Zhang, Dawei
    Ban, Qiaoying
    PLANT MOLECULAR BIOLOGY REPORTER, 2008, 26 (03) : 241 - 254
  • [32] Analysis of Gene Expression Profile of Limonium bicolor under NaHCO3 Stress Using cDNA Microarray
    Yucheng Wang
    Hui Ma
    Guifeng Liu
    Chenxi Xu
    Dawei Zhang
    Qiaoying Ban
    Plant Molecular Biology Reporter, 2008, 26 : 241 - 254
  • [33] The gene expression profile of human umbilical vein endothelial cells stimulated with lipopolysaccharide using cDNA microarray analysis
    Ahn, SK
    Choe, TB
    Kwon, TJ
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2003, 12 (02) : 231 - 236
  • [34] cDNA microarray analysis of global gene expression in sarcomas
    Schofield, D
    Triche, TJ
    CURRENT OPINION IN ONCOLOGY, 2002, 14 (04) : 406 - 411
  • [35] CDNA microarray gene expression analysis of seminal vesicles
    Purohit, RS
    Khodabakhsh, DB
    Kakefuda, M
    Haqq, C
    JOURNAL OF UROLOGY, 2003, 169 (04): : 363 - 363
  • [36] cDNA microarray analysis of pigment epithelium-derived factor-regulated gene expression profile in prostate carcinoma cells
    Liu, Weiwei
    Wu, Zhong
    Guan, Ming
    Lu, Yuan
    INTERNATIONAL JOURNAL OF UROLOGY, 2009, 16 (03) : 323 - 328
  • [37] Gene microarray analysis of the lncRNA expression profile in human urothelial carcinoma of the bladder
    Luo, Huarong
    Zhao, Xin
    Wan, Xiaodong
    Huang, Shengsong
    Wu, Denglong
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2014, 7 (05): : 1244 - 1254
  • [38] Pathway Crosstalk Analysis of Microarray Gene Expression Profile in Human Hepatocellular Carcinoma
    Zhou, Xiaodong
    Zheng, Ruiguo
    Zhang, Huifang
    He, Tianlin
    PATHOLOGY & ONCOLOGY RESEARCH, 2015, 21 (03) : 563 - 569
  • [39] Gene expression profile of mouse bone marrow stromal cells determined by cDNA microarray analysis
    Georg Wieczorek
    Christine Steinhoff
    Ralph Schulz
    Marina Scheller
    Martin Vingron
    H.-Hilger Ropers
    Ulrike A. Nuber
    Cell and Tissue Research, 2003, 311 : 227 - 237
  • [40] DHA effect on gene expression profile in human fetal retinal explants: cDNA microarray analysis
    Cecilia, RV
    Jessica, M
    Dennis, H
    Ricardo, U
    PEDIATRIC RESEARCH, 2002, 51 (04) : 286A - 287A
12345