Astragalus polysaccharide enhances immunity and inhibits H9N2 avian influenza virus in vitro and in vivo

被引：46

作者：

Sanpha Kallon ^{[1
]}

Xiaorong Li ^{[1
]}

Jun Ji ^{[1
]}

Cuiying Chen ^{[1
]}

Qianyun Xi ^{[1
]}

Shuang Chang ^{[2
]}

Chunyi Xue ^{[3
]}

Jingyun Ma ^{[1
]}

Qingmei Xie ^{[1
]}

Youngliang Zhang ^{[1
]}

机构：

[1] College of Animal Science, South China Agricultural University

[2] US Department of Agriculture, Agricultural Research Service, Avian Disease and Oncology Laboratory

[3] State Key Laboratory of Biocontrol, College of Life Sciences, Sun Yat-Sen University

来源：

Journal of Animal Science and Biotechnology | 2013年 / 4卷 / 04期

关键词：

Astragalus polysaccharide; H9N2 avian influenza virus; Immune effect;

D O I：

暂无

中图分类号：

S852.65 [家畜病毒学];

学科分类号：

090601 ;

摘要：

This study investigated the humoral immunization of Astragalus polysaccharide(APS) against H9N2 avian influenza virus(H9N2 AIV) infection in chickens. The effects of APS treatment on H9N2 infection was evaluated by an MTT [3(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide] assay and analysis of MHC and cytokine mRNA expression. The effect on lymphocyte and serum antibody titers in vivo was also investigated. IL-4, IL-6, IL-10, LITAF, IL-12 and antibody titers to H9N2 AIV were enhanced in the first week after APS treatment. The results indicated that APS treatment reduces H9N2 AIV replication and promotes early humoral immune responses in young chickens.

引用

页码：325 / 335

页数：11

共 50 条

[41] Phylogeography of Avian influenza A H9N2 in China
Jin, Yuan
Yu, Dong
Ren, Hongguang
Yin, Zhiqiu
Huang, Zhisong
Hu, Mingda
Li, Beiping
Zhou, Wei
Yue, Junjie
Liang, Long
BMC GENOMICS, 2014, 15
[42] Evaluation of pathogenic potential of avian influenza virus serotype H9N2 in chickens
Bano, S
Naeem, K
Malik, SA
AVIAN DISEASES, 2003, 47 : 817 - 822
[43] Human Infection with Avian Influenza A(H9N2) Virus, Cambodia, February 2021
Um, Samnang
Siegers, Jurre Y.
Sar, Borann
Chin, Savuth
Patel, Sarika
Bunnary, Seng
Hak, Makara
Sor, Sothy
Sokhen, Oum
Heng, Seng
Chau, Darapheak
Sothyra, Tum
Khalakdina, Asheena
Mott, Joshua A.
Olsen, Sonja J.
Claes, Filip
Sovann, Ly
Karlsson, Erik A.
EMERGING INFECTIOUS DISEASES, 2021, 27 (10) : 2742 - 2745
[44] Chicken anaemia virus enhances and prolongs subsequent avian influenza (H9N2) and infectious bronchitis viral infections
Erfan, Ahmed M.
Selim, Abdullah A.
Helmy, Shawky A.
Eriksson, Per
Naguib, Mahmoud M.
VETERINARY MICROBIOLOGY, 2019, 230 : 123 - 129
[45] Evaluation of Transmission Route and Replication Efficiency of H9N2 Avian Influenza Virus
Shi, Huoying
Ashraf, Shamaila
Gao, Song
Lu, Jianhong
Liu, Xiufan
AVIAN DISEASES, 2010, 54 (01) : 22 - 27
[46] Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea
Heo, Gyeong-Beom
Kye, Soo-Jeong
Sagong, Mingeun
Lee, Eun-Kyoung
Lee, Kwang-Nyeong
Lee, Yu-Na
Choi, Kang-Seuk
Lee, Myoung-Heon
Lee, Youn-Jeong
JOURNAL OF VETERINARY SCIENCE, 2021, 22 (02) : 1 - 6
[47] Human infection with an avian influenza A (H9N2) virus in the middle region of China
Huang, Yiwei
Li, Xiaodan
Zhang, Hong
Chen, Bozhong
Jiang, Yonglin
Yang, Lei
Zhu, Wenfei
Hu, Shixiong
Zhou, Siyu
Tang, Yunli
Xiang, Xingyu
Li, Fangcai
Li, Wenchao
Gao, Lidong
JOURNAL OF MEDICAL VIROLOGY, 2015, 87 (10) : 1641 - 1648
[48] Genetic evolution of the H9N2 avian influenza virus in Korean poultry farms
Lee, Chang-Hee
Byun, Sung-Hwan
Lee, Youn-Jeong
Mo, In-Pil
VIRUS GENES, 2012, 45 (01) : 38 - 47
[49] Identification of avian influenza virus subtype H9N2 in chicken farms in Indonesia
Jonas, Melina
Sahesti, Aprilla
Murwijati, Theresia
Lestariningsih, Christina Lilis
Irine, Ine
Ayesda, Clara Sinta
Prihartini, Wahyu
Mahardika, Gusti Ngurah
PREVENTIVE VETERINARY MEDICINE, 2018, 159 : 99 - 105
[50] Pathogenesis and Immunogenicity of an Avian H9N2 Influenza Virus Isolated from Human
Liu LiQi
Li Zi
Zhou JianFang
Zhu Yun
Dong Jie
Zhao Xiang
Guo JunFeng
Shu YueLong
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2011, 24 (05) : 530 - 536

← 1 2 3 4 5 →